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  • Ipatasertib

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    Ipatasertib (Roche) is a highly selective, ATP-competitive Akt inhibitor that preferentially targets active, phosphorylated Akt.

    February 26, 2020
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  • lyrica report

    Lynparza

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    Lynparza (olaparib; AstraZeneca) is a small molecule poly (ADP-ribose) polymerase (PARP) inhibitor. The PARP enzyme plays a central role in a number of cellular processes involved in cellular homeostasis.

    February 26, 2020
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  • keytruda report

    Keytruda

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    Keytruda is a humanized monoclonal antibody designed to inhibit the PD-1 co-inhibitory receptor. The interaction between PD-1 and its primary ligand, PD-L1, inhibits T-cell proliferation and survival, and induces apoptosis of tumor-specific T-cells.

    February 26, 2020
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  • Halaven

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    Halaven (eribulin mesylate; Eisai) is a synthetic macrocyclic ketone analog of halichondrin B that acts as a tubulin depolymerizer and functionally inhibits tumor cell proliferation with arrest in the G2-M phase of cell growth. B

    February 26, 2020
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  • juxtapid report

    Juxtapid

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    Juxtapid (lomitapide mesylate) is a novel, first-in-class microsomal triglyceride transfer protein (MTP) inhibitor marketed by Aegerion.

    November 20, 2019
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  • Inclisiran

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    Inclisiran (The Medicines Company/Alnylam Pharmaceuticals) is a systemically delivered siRNA therapeutic targeting mRNA for PCSK.

    November 20, 2019
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  • Imfinzi

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    Imfinzi (durvalumab; AstraZeneca)  is a human monoclonal antibody directed against programmed death-ligand 1 (PD-L1).

    September 9, 2019
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  • Lenvima

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    Lenvima (lenvatinib; Eisai/Novartis/Merck & Co) is an orally available small molecule inhibitor of multiple tyrosine kinases including vascular endothelial growth factor receptor (VEGFR), platelet-derived growth factor receptor (PDGFR), and fibroblast growth factor receptor (FGFR).

    September 9, 2019
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  • Juluca

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    Juluca ([dolutegravir + rilpivirine]; ViiV Healthcare/Johnson & Johnson) is a single-tablet regimen approved in the US for the treatment of patients infected with HIV-1 who have achieved viral suppression.

    June 28, 2019
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  • leronlimab

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    Leronlimab (CytoDyn) is a humanized monoclonal antibody directed against C-C chemokine receptor 5 (CCR5), which is a co-receptor required for the attachment and entry of CCR5-tropic HIV-1 viruses into host cells.

    June 28, 2019
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  • Isentress

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    Isentress (raltegravir; Merck & Co) is a twice-daily, unboosted integrase inhibitor (INI) that is used in combination with other antiretroviral drugs for treatment of HIV-1 infection.

    June 28, 2019
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  • Genvoya

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    Genvoya (elvitegravir/cobicistat/emtricitabine/tenofovir alafenamide fumarate [TAF]; Gilead) is a single-tablet regimen (STR) approved for the treatment of HIV-1 infection.

    June 28, 2019
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  • lexapro report

    Lexapro

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    Lexapro (escitalopram; Allergan/Lundbeck/Mitsubishi Tanabe/Mochida) is a selective serotonin reuptake inhibitor, and acts by blocking the re-uptake of serotonin.

    March 29, 2019
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  • Latuda

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    Latuda (lurasidone; Sumitomo Dainippon/Angelini) contains the atypical antipsychotic lurasidone, which acts as an antagonist of dopamine receptors D2, and serotonin receptors 5-HT2A. By inhibiting the synaptic reuptake of dopamine and serotonin, Latuda helps to normalize brain activity and reduce schizophrenia symptoms.

    March 29, 2019
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  • Inlyta

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    Inlyta (axitinib; Pfizer) is a kinase inhibitor designed to selectively inhibit vascular endothelial growth factor receptor-1.

    March 6, 2019
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