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You are here: Home > Strategy analysis > KOL Insight

KOL Insight


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  • Aromatase Resistance and Palbociclib for Breast Cancer

    $89.00

    These pathways can be targeted either at the cell surface receptor

    level or their downstream signaling cascades. Currently, everolimus in combination with

    exemestane represents a new standard of care for patients progressing on non-steroidal AIs.

    HDAC inhibitors have also shown promising results For innate resistance, the combination of

    fulvestrant and AI in the front line setting represents a new treatment option, particularly for

    patients who present with de novo metastatic disease.

    April 1, 2014
    Find out more
  • Macitenan for Pulmonary Arterial Hypertension

    $89.00

    Macitentan is a novel dual endothelin receptor antagonist (ERA)

    showing sustained receptor occupancy

    March 1, 2014
    Find out more
  • Tyvaso for Pulmonary Arterial Hypertension

    $89.00

    The literature search was undertaken via multiple search engines and strategies with review of cited and associated articles to provide a comprehensive discussion on the topic. Expert opinion: While safe and well tolerated, inhaled treprostinil sodium should be limited, based on available data, to use as add-on therapy for patients with Group I pulmonary hypertension not effectively controlled on oral therapy.

    November 29, 2016
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  • Palbociclib for Breast Cancer

    $89.00

    Palbociclib (PD 0332991): targeting the cell cycle machinery in breast cancer

    February 1, 2014
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  • Selexipag for Pulmonary Arterial Hypertension

    $89.00

    Areas covered: Selexipag is rapidly hydrolyzed to an active metabolite, ACT-333679. Both selexipag and its metabolite are highly selective for the IP receptor compared with other prostanoid receptors. This selectivity for the IP receptor offers the potential for improved tolerability with selexipag, as side effects (e.g., nausea and vomiting) that might result from activation of the other prostanoid receptors may be minimized.

    February 1, 2014
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  • Alzheimer’s KOL Interview

    $399.00

    KOL is optimistic on amyloid-targeted therapy and believes IV therapy will be tolerated if approved.

    October 21, 2015
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  • Inpatient Infections Pulse

    $599.00

    We conducted a survey of 20 infectious diseases specialists to evaluate current drug usage for the treatment of selected severe/inpatient infections and gauge physician interest in new drugs.

    October 8, 2014
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  • 2015 Post-AAIC KOL Interview

    $599.00

    Following the 2015 Alzheimer’s Association International Conference (AAIC), we interviewed an Alzheimer’s Disease expert on his opinion of the data presentations and the future of Alzheimer’s Disease treatment.

    August 1, 2015
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  • Datamonitor-Acute-Myelogenous-Leukemia-KOL-Interview

    Acute Myelogenous Leukemia (AML) KOL Interview

    $599.00

    Datamonitor interviewed three oncology specialists to determine the physicians’ views on marketed and pipeline therapies for Acute Myelogenous Leukemia. Two physicians were based in the US (Greater Midwest and Greater Boston areas) and one in the UK. The three interviews were combined into a single report.

    August 19, 2016
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  • Post-EASL KOL Interview

    $599.00

    Highlights KOL believes elsbasvir and grazoprevir data will lead to approval and look similar to available drugs on the market (MRK). Post-liver transplant data for sofosbuvir and simpeprevir was positive (GLD, JNJ). Three DAA combination of -5816,-9857, and sofosbuvir looked good, but most physicians are erring on the side of conservative 12- week treatment regimens […]

    May 29, 2015
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  • pcsk9-inhibitors

    2015 PCSK9 Inhibitors Pulse

    $599.00

    Following the approval of the first PCSK9 Inhibitor, Praluent (SNY, REGN), this 5- question survey of 23 cardiologists evaluated attitudes towards the class, projected usage prior to their CVOTs depending on insurance prior authorization, preference of Praluent vs Repatha (AMGN), and how the oral CETP inhibitors would impact PCSK9 usage under different outcomes study scenarios.

    August 19, 2015
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  • Breast Cancer Pulse #2

    $599.00

    We performed a 5-question survey of 24 oncologists in the US to gauge current prescribing practices for breast cancer treatments, with a focus on HR+/HER2- recurrent or metastatic breast cancer. Drugs and drug candidates discussed: •Neratinib, PBYI •Herceptin (trastuzumab), Roche •Perjeta (pertuzumab), Roche •Kadcyla (trastuzumab-DM1), Roche •Tykerb (lapatinib), GSK

    October 31, 2016
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  • Breast Cancer Pulse #1

    $599.00

    We performed a 5-question survey of 22 oncologists in the US to gauge current prescribing practices for breast cancer treatments, with a focus on HR+/HER2- recurrent or metastatic breast cancer. Drugs discussed: •Ibrance (palbociclib, PFE) •Afinitor (everolimus, NVS) •Halaven (eribulin, Eisai) •Abraxane (nab-paclitaxel, CELG) •Doxil (pegylated liposomal doxorubicin, JNJ) •Gemzar (gemcitabine, LLY) •Xeloda (capecitabine, Roche)

    October 31, 2016
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  • 2016 Biomedtracker ASCO Survey

    $599.00

    Biomedtracker performed a 5-question survey of 39 United States and European (France, Germany, Italy, and United Kingdom) oncologists after the American Society of Clinical Oncology (ASCO) meeting to gauge interest in new data presented on drugs in clinical development.

    June 8, 2016
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  • MDS/AML KOL Interview

    $599.00

    Highlights More specific, next-generation FLT3 inhibitors may not have an anti-leukemic benefit over agents with broader TKI activity (such as sorafenib, AMGN), but they may not have as severe myelosuppressive effects. Although the kinase inhibitor rigosertib (ONTX) had poor Phase III results in MDS and AML, the subgroup of patients with primary HMA failure may […]

    April 9, 2015
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  • 2015-cll-pulse-2-drug-usage-and-reimbursement

    2015 Chronic Lymphocytic Leukemia (CLL) Pulse

    $599.00

    We performed a 5-question survey of 40 hematology-oncology specialists in the US to gauge current prescribing practices and physician experience with reimbursement for ibrutinib and idelalisib for the treatment of patients with CLL.

    January 27, 2015
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  • dysliidemia-kol

    Dyslipidemia and Diabetes Reimbursement KOL Interview:

    $599.00

    Topics: Dyslipidemia and Diabetes Reimbursement PCSK9 Inhibitors, SGLT2/DPP4 Inhibitor FDCs, and Biosimilar Insulin

    August 5, 2015
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  • Post-ADPD Alzheimer’s Disease KOL Interview

    $599.00

    Key Highlights BIIB-037 Amyloid beta PET data show positive Abeta reduction; cognitive results are not interpretable with such small numbers. (BIIB) BIIB-037 Phase Ib result interpretation may be effected by the ApoE4 dropouts in the treatment arm. (BIIB) MK-8931 and BIIB-037 show sufficient target engagement, but there is no evidence to date that amyloid clearance […]

    April 8, 2015
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  • Pediatric Acute Leukemias (AML/ALL) KOL Interview

    $599.00

    Highlights Current manufacturing turnaround times for CAR-T products (2-3 weeks) for ALL are not a major limitation for pediatric leukemia patients. CAR-T treatments may be more acutely toxic than transplant immediately after infusion, but patients may have fewer medium- and long-term complications. Agents that target the cell cycle (CDK inhibitors, Aurora kinase inhibitors) will likely […]

    April 1, 2015
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  • biosimilars-and-reimbursement

    Biosimilars and Reimbursement KOL Interview

    $599.00

    Topics: Biosimilars and Reimbursement

    Physician Information

    Specialty: Specialty Pharmaceuticals

    Location: Alexandria, VA

    July 31, 2015
    Find out more
  • ADPD Alzheimer’s Disease Pulse

    $599.00

    Overview We performed a 5-question survey of 25 neurologists in the US to gauge current familiarity with Alzheimer’s Disease (AD) biomarkers and drugs in clinical development for disease modification. Drugs covered include: BIIB037/BART (BIIB), Solanezumab (LLY), Pioglitazone (Takeda), BAN2401 (ESALY/BIIB), MK-8931 (MRK).

    March 19, 2015
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  • Pneumococcal Vaccines KOL Interview

    $599.00

    Datamonitor interviewed three infectious diseases specialists to determine the physicians’ views on marketed and pipeline pneumococcal vaccines. Two physicians were based in Chicago, IL and one in the UK. The three interviews were combined into a single report.

    August 27, 2016
    Find out more
  • Asthma and COPD KOL Interview

    $599.00

    KOL thinks that the biggest challenge to treating COPD is cost, even with a very low population of uninsured people.

    February 29, 2016
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  • 2014 Community-Acquired Pneumonia Pulse

    $599.00

    We performed a 5-question survey of 20 infectious disease (ID) specialists in the U.S. to gauge current prescribing practices for community-acquired pneumonia (CAP) and gauge interest in new drugs/new drug candidates.

    December 18, 2014
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  • Post-AASLD US KOL Interview

    $599.00

    Over 95% SVR for easy-to-treat patients, and it’s one pill a day for 8-12 weeks for most. In that context, the only way you can improve up on that is to improve care for all populations, not just for easy-to-treat but the difficult-to-treat: decompensated cirrhotics, the post-transplant, and HIV co-infected patients.

    December 16, 2014
    Find out more
  • Ebola KOL Interview #3

    $599.00

    Ebola KOL Interview #3

    December 2, 2014
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  • 2015 Breast Cancer Pulse #3

    $599.00

    We performed a 5-question survey of 25 oncologists in the US to gauge current prescribing practices for breast cancer treatments.

    June 12, 2015
    Find out more
  • Drug Pricing and Market Access KOL Interview

    $599.00

    Expensive oncology treatments [PD-1 and upcoming CAR-T therapies] will continue to be covered by large insurers formularies, but access will be restricted according to NCCN guidelines.

    February 1, 2016
    Find out more
  • Intersection Between Tech and Pharma KOL Interview

    $599.00

    Given the rapid change in the healthcare industry over the last few years, it is no surprise that we are starting to see more non-traditional healthcare partnerships, specifically with big tech companies.

    January 12, 2016
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  • 2015 Jardiance EMPA-REG CVOT Pulse

    $599.00

    This 5-question survey of 30 primary care physicians and 29 endocrinologists in the United States evaluates the impact of the EMPA-REG cardiovascular outcomes trial (CVOT) of SGLT2 inhibitor Jardiance (Boehringer, LLY).

    November 1, 2015
    Find out more
  • Treatment of VTE – EU KOL Interview

    $599.00

    This interview with an EU vascular physician explores the dynamics in the 5 major European markets regarding the introduction of novel/direct oral anticoagulants (NOAC, DOAC) in the treatment of venous thromboembolism (VTE) and prevention of recurrence.

    November 4, 2015
    Find out more
  • Treatment of VTE – US KOL Interview

    $599.00

    This interview with a US hematologist focuses on the changing dynamics with the introduction of novel/direct oral anticoagulants (NOAC, DOAC) in the treatment of venous thromboembolism (VTE) and prevention of recurrence.

    November 2, 2015
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  • Datamonitor Schizophrenia KOL Interview 2

    $599.00

    KOL believes that the available schizophrenia treatments that provide the most efficacy also have the highest side effects.

    February 24, 2016
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  • Datamonitor Schizophrenia KOL Interview

    $599.00

    On key factors effecting treatment: “First of all tolerability, because if the tolerability is not good then there will be no adherence. The second is efficacy, and the third one maybe is also whether the compound is also available as a depot. I think that is a major advantage if a drug, if an antipsychotic, is indeed available as a depot or as a long-acting injection (LAI).”

    February 10, 2016
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  • Triple Negative Breast Cancer KOL Interview

    $599.00

    “It [Abraxane] is so easy to give. Women tolerate it so well. It works pretty good, it doesn’t work all the time, it works pretty well, and the patients don’t get so fatigued, they don’t have side effects, they don’t need premeds, and they rarely need to be boosted for white cells decrease. Whereas in the Eribulin, you know they’re gonna be coming back. It’s a pretty easy drug to give. Patients tolerate it fairly well… I use it [Abraxane] as first line and I go back to it. Even if I have somebody that progresses, if they’ve been off of it for a while, I will often even go back to it.”

    February 9, 2016
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  • Acute Lymphocytic Leukemia KOL Interview

    $599.00

    [Newer treatments] are definitely being used in the relapse population, and that’s where they made their mark like most other investigational agents for other cancers. I think the issue is that the response rate with initial induction therapy is so high. Whether or not there is going to be a maintenance-type study strategy, that’s a question with some of these therapies that are relatively low toxicity, but when you have a complete remission rate of 90-95%, and ALL’s not the most common disease – it’s a pretty rare cancer actually – that it’s going to be difficult to do large studies for indications in the randomized setting.

    February 9, 2016
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  • Follicular Lymphoma KOL Interview

    $599.00

    “When people need therapy (for advanced stage Follicular Lymphoma), there’s a whole gamut. If they have relatively low volume disease, one option, which unfortunately in the community I would say is underutilized, is single-agent rituximab.”

    February 3, 2016
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  • GLP-1 Pulse Survey

    $599.00

    This survey of US primary care physicians (n=10) and endocrinologists (n=10) was undertaken to evaluate the impact of GLP-1 agonists if they were to be introduced in the Diabetes market.

    August 25, 2014
    Find out more
  • SGLT-2 Pulse Survey

    $599.00

    We surveyed primary care physicians (n=10) and endocrinologists (n=10) to see how SGLT-2 inhibitors and the combo pills will be used and what the potential impact of usage with GLP-1 agonists may have.

    August 25, 2014
    Find out more
  • Datamonitor Meningococcal Vaccines KOL Interview

    $599.00

    Datamonitor interviewed an infectious diseases specialist based in the US Greater Washington DC area to determine this physician’s views on marketed and pipeline meningococcal vaccines.

    July 12, 2016
    Find out more
  • 2016 Biomedtracker Post-EASL Hepatitis C Survey

    $599.00

    We performed a 9-question survey of 29 EU and 31 US hepatologists and gastroenterologists after the European Association of the Study of the Liver (EASL) International Liver Conference (ILC) from April, 2016 in Barcelona to gauge current and projected prescribing practices for hepatitis C virus (HCV) infection.

    May 16, 2016
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  • Biomedtracker Diabetic Nephropathy/Diabetic Kidney Disease KOL Interview

    $599.00

    Biomedtracker interviewed a nephrologist based in the US Midwest to determine his views on the drugs in development for diabetic nephropathy/diabetic kidney disease.

    May 13, 2016
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  • Biomedtracker Entresto Pulse

    $599.00

    Uptake of Entresto (NVS) in the US has been slow following approval in July 2015. Part of that is due to the time it has taken to secure insurance coverage, but physicians have complained about other insurance barriers, as well, and there are also clinical factors that could play a role.

    May 11, 2016
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  • 2015 Breast Cancer Pulse #2

    $599.00

    This 5-question pulse of 24 oncologists practicing in the United States focuses on the usage of HER2-targeted agents for the treatment of breast cancer.

    May 26, 2015
    Find out more
  • 2015 Breast Cancer Pulse #1

    $599.00

    This five-question survey of oncologists focuses on treatments for metastatic or locally advanced, HR+/HER2- breast cancer.

    May 13, 2015
    Find out more
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