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Trends in CNS Dealmaking, 2012–16

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Diseases of the central nervous system (CNS) offer considerable opportunity to drug developers and marketers.

August 8, 2017

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Gene Editing: The Next Breakthrough in Regenerative Medicine

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Believed to be one of the great biotechnology breakthroughs, gene editing is a powerful tool in pharmaceutical research that could radically change how certain diseases are treated.

September 1, 2017

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Acute Myeloid Leukemia Pricing, Reimbursement, and Access

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The level of concern surrounding the budget impact of acute myeloid leukemia (AML) has traditionally been low due to the relatively small size of the population in comparison to solid tumors, the high severity of the disease, and a lack of branded treatment options. As a result, few access controls are utilized for AML therapies. […]

December 15, 2017

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Orphan Drug Access and Pricing in Emerging Markets

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This analysis covers the four major emerging regions of the Middle East and Africa, Latin America, Eastern Europe, and Asia-Pacific. Within these regions, relatively wealthier markets with a proven marketplace for orphan medicines have been prioritized.

January 12, 2018

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Biosimilars Market Access in the EU

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Biosimilars have been available in Europe for over a decade, and have offered the opportunity to vastly reduce the cost of treatment for a large number of biologic agents.

January 19, 2018

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Latest Trends in Orphan Drug Pricing and Reimbursement

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It is now some 35 years since the passage of the first law designed specifically to encourage investment in the discovery and development of rare disease treatments. Activity in the sector has been transformed since then.

February 1, 2018

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Gene Therapy Deal-Making Trends, 2012–17

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A robust deal-making market has enabled gene therapy drug development to be advanced and adequately funded through alliances and financings, and in many cases has provided exits for investors through acquisitions.

February 14, 2018

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Ovarian Cancer Pricing, Reimbursement, and Access

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Ovarian cancer medicines have traditionally been subject to low restrictions, as most patients usually start and remain on inexpensive platinum-based therapies. However, beginning with the launch of vascular endothelial growth factor inhibitor Avastin, followed by poly (ADP-ribose) polymerase (PARP) inhibitor Lynparza, payers are seeing an uptick in spend for the indication.

March 5, 2018

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Crohn’s Disease and Ulcerative Colitis Pricing, Reimbursement, and Access

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Payers view spending on inflammatory bowel disease (IBD) drugs as significant, as there is a large patient base requiring expensive biologic therapies. The market has been long dominated by the TNF-alpha inhibitors Humira and Remicade, but more recent biologic launches such as Entyvio and Stelara have focused on novel mechanisms of action.

March 16, 2018

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Chronic Heart Failure Pricing, Reimbursement, and Access

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Payers were originally extremely worried about the potential cost burden of Entresto, however, the level of concern surrounding the drug is currently moderate as physician uptake has been lower than expected.

April 13, 2018

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prostate-cancer-pricing-reimbursement-and-access_162106_10-2016

Prostate Cancer: Market Access Pricing & Reimbursement

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The prostate cancer market has become saturated in the metastatic castration-resistant prostate cancer (CRPC) setting; the approval of second-generation antiandrogens, radiotherapies, and chemotherapies has resulted in a great deal of development targeting earlier stages of the disease.

June 1, 2018

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Digital Pharma: Are We Nearly There?

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Digital’s potential to transform every aspect of the pharmaceutical value chain, from discovery to commercial, is widely documented.

August 14, 2018

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Renal Cell Cancer Pricing, Reimbursement, and Access

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There is moderate concern among payers regarding spend on renal cell cancer (RCC) drugs, but access restrictions remain mild.

August 22, 2018

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Value-Based Reimbursement in the US

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The US healthcare environment has been witnessing a slow albeit continuous shift from volume- to value-based reimbursement over the past couple of decades

August 22, 2018

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Bladder Cancer Pricing, Reimbursement, and Access

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Payers are not overly worried about the cost of bladder cancer, due to the relatively small patient population in comparison to other solid tumors.

September 27, 2018

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