Arcapta
Publisher: Datamonitor Healthcare
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Drug Overview
Novartis has developed Arcapta (indacaterol; marketed as Onbrez outside the US) for use in its Breezhaler/Neohaler dry-powder inhaler for the treatment of chronic obstructive pulmonary disease (COPD). As the first once-daily long-acting beta 2 agonist (LABA) to launch in the COPD market, Arcapta has seen high use as an add-on therapy to the gold-standard long-acting muscarinic antagonist (LAMA), Spiriva (tiotropium; Boehringer Ingelheim). Due to the increasing availability of fixed-dose LABA/LAMA combination therapies, including Sunovion and Novartis’s Utibron Neohaler ([indacaterol + glycopyrrolate]), and a number of triple-combination therapies having been launched, Datamonitor Healthcare does not forecast Arcapta to continue being used as an add-on therapy to Spiriva or other LAMA monotherapies. Instead, Arcapta is expected to be predominantly used as a monotherapy in mild and moderate patients.
TABLE OF CONTENTS
4 OVERVIEW
4 Drug Overview
5 Product Profiles
5 Arcapta Neohaler : Chronic obstructive pulmonary disease (COPD)
LIST OF FIGURES
9 Figure 1: Arcapta for COPD – SWOT analysis
10 Figure 2: Datamonitor Healthcare’s drug assessment summary of Arcapta for COPD
11 Figure 3: Datamonitor Healthcare’s drug assessment summary of Arcapta for COPD
13 Figure 4: Arcapta Neohaler sales for COPD across Japan and the five major EU markets, by country, 2017–26
LIST OF TABLES
5 Table 1: Arcapta drug profile
7 Table 2: Arcapta Phase III data in COPD
14 Table 3: Arcapta Neohaler sales for COPD across Japan and the five major EU markets, by country ($m), 2017–26
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