Explore what happens when a drug loses its Breakthrough Therapy Designation (BTD) from the FDA. Pink Sheet examines some recent rejects from the BTD list and follows their trajectories after the loss of the label – does it mean the end of the line, or just a new path for the drugs? Pink Sheet’s experts also take a look at other therapies that may soon be due to lose their BTD status, and probes the reasons driving these possible upcoming withdrawals and rescissions.