Crohn’s Disease: Epidemiology
Crohn’s Disease: Epidemiology
Crohn’s disease involves inflammation of the gastrointestinal (GI) tract, and most commonly affects the terminal ileum or colon.
Author: Nicola Sawalhi-Leckenby
Publisher: Datamonitor Healthcare
This epidemiologic analysis uses robust, country-specific data sources to estimate and forecast diagnosed prevalent cases of Crohn’s disease (CD) in the US, Japan, and five major EU markets (France, Germany, Italy, Spain, and the UK) between 2015 and 2035.
Datamonitor Healthcare epidemiologists present estimates and forecasts by age and gender.
Datamonitor Healthcare estimates that in 2015, there were 1.4 million diagnosed prevalent cases of CD in the US, Japan, and five major EU markets. The majority of cases were in those aged 30–69 years.
Datamonitor Healthcare estimates that the US had the highest number of prevalent CD cases of the analyzed markets in 2015, while the lowest number was in Japan. Over the forecast period (2015–35), the number of prevalent cases of CD will increase in the US and five major EU markets, while cases will slightly decrease in Japan.
An epidemiology datapack accompanies this module, which includes 20-year forecasts of CD cases segmented by age and gender.
Proprietary epidemiologic forecasting methodology using robust, population-based studies from the US, Japan, and five major EU markets.
TABLE OF CONTENTS
6 DISEASE BACKGROUND
6 Inflammatory bowel disease is a term used to describe disorders that involve inflammation of the gastrointestinal tract
6 Inflammatory bowel disease mainly encompasses ulcerative colitis and Crohn’s disease
6 The etiology of inflammatory bowel disease remains to be determined, although genetic and environmental factors play a role
7 Compounding prevalence is a phenomenon that continues to add to the inflammatory bowel disease case pool
8 Crohn’s disease is a type of inflammatory bowel disease that may affect any part of the gastrointestinal tract
8 The clinical presentation and observed phenotype of Crohn’s disease varies by age
9 Crohn’s disease is currently an idiopathic condition, with increased mortality relative to the general population
10 Disease definition
10 Data sources
16 Data assumptions and approach to trending
20 Diagnosed prevalent cases of Crohn’s disease
APPENDIX: ADDITIONAL SOURCES
LIST OF FIGURES
24 Figure 1: Trends in diagnosed prevalent cases of Crohn’s disease in the US, Japan, and five major EU markets, by country, 2017–37
LIST OF TABLES
7 Table 1: Inflammatory bowel disease risk factors
9 Table 2: Montreal classification of Crohn’s disease
11 Table 3: Sources used for Crohn’s disease analysis in the US, Japan, and five major EU markets
17 Table 4: Crohn’s disease data processing methods in the US, Japan, and five major EU markets
21 Table 5: Diagnosed prevalent cases of Crohn’s disease in the US, Japan, and five major EU markets, by country, 2017–37
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