CONTENTS

Executive Summary ………………………………………………………………………. ES‐1
i. Cardiac rhythm disorder overview………………………………………………………………………….ES‐1
ii. Global electrocardiograph (ECG) device market………………………………………………………ES‐1
a. Market drivers and limiters……………………………………………………………………….ES‐3
b. Device segment insights …………………………………………………………………………..ES‐4
c. Technology trends……………………………………………………………………………………ES‐5
d. Market leaders………………………………………………………………………………………..ES‐6
e. Competitive strategies……………………………………………………………………………..ES‐6
f. Emerging competition ………………………………………………………………………………ES‐6
iii. Methodology……………………………………………………………………………………………………..ES‐6

Exhibit ES‐1: Diagnostic ECG products, global market forecast, 2017‐22 …………………………………..ES‐2
Exhibit ES‐2: Global diagnostic ECG products market, share by country/region, 2017…………………ES‐3
Exhibit ES‐3: Diagnostic ECG products market growth drivers and limiters………………………………..ES‐4

1. Cardiac Rhythm Disorders……………………………………………………………..1‐1
1.1 Bradycardia ………………………………………………………………………………………………………. 1‐3
1.2 Sick sinus syndrome…………………………………………………………………………………………… 1‐3
1.3 Heart block……………………………………………………………………………………………………….. 1‐3
1.4 Tachycardia ………………………………………………………………………………………………………. 1‐5
1.5 Atrial fibrillation ………………………………………………………………………………………………… 1‐6
1.6 Heart failure ……………………………………………………………………………………………………… 1‐7
1.7 Myocardial infarction…………………………………………………………………………………………. 1‐8
1.8 Syncope……………………………………………………………………………………………………………. 1‐9
1.9 Diagnosis and indications for ECG ……………………………………………………………………….. 1‐9
1.10 Bibliography ………………………………………………………………………………………………….. 1‐11

Exhibit 1‐1: Estimated prevalence rates of conduction disorders and cardiac arrhythmias across the US, Japan, and five major EU markets………………………………………………….. 1‐2
Exhibit 1‐2: Estimated prevalence of atrial fibrillation, selected countries, 2017………………………… 1‐7
Exhibit 1‐3: Types of syncope and associated causes………………………………………………………………. 1‐9

2. Electrocardiograph Products……………..
2.2 Implantable loop recorders ………………………………………………………………………………. 2‐11
2.3 Consumer self‐monitoring products…………………………………………………………………… 2‐12
2.4 Bibliography ……………………………………………………………………………………………………. 2‐14

Exhibit 2‐1: Average electrocardiogram tracing ……………………………………………………………………… 2‐2
Exhibit 2‐2: ECG basics………………………………………………………………………………………………………… 2‐3
Exhibit 2‐3: Selected resting ECG products and manufacturers………………………………………………… 2‐4
Exhibit 2‐4: Selected exercise/stress testing ECG products and manufacturers………………………….. 2‐6
Exhibit 2‐5: Comparative advantages and disadvantages of ambulatory ECG devices…………………. 2‐7
Exhibit 2‐6: Selected Holter monitor products and manufacturers …………………………………………… 2‐8
Exhibit 2‐7: Selected event loop recorder products and manufacturers ……………………………………. 2‐9
Exhibit 2‐8: Selected Implantable loop recorder products and manufacturers…………………………. 2‐12
Exhibit 2‐9: Selected consumer rhythm management products and manufacturers…………………. 2‐13

3. Diagnostic Electrocardiograph Products Market………………………………..3‐1
3.1 Global market insights……………………………………………………………………………………….. 3‐1
3.1.1 Market value………………………………………………………………………………………. 3‐1
3.1.2 Technology trends ………………………………………………………………………………. 3‐5
3.1.3 Market drivers and limiters ………………………………………………………………….. 3‐5
3.1.4 Products overview ………………………………………………………………………………. 3‐7
3.1.5 Market leaders……………………………………………………………………………………. 3‐8
3.1.6 Competitive strategies…………………………………………………………………………. 3‐8
3.1.7 Emerging competition …………………………………………………………………………. 3‐9
3.2 Global competitors ……………………………………………………………………………………………. 3‐9
3.2.1 Resting ECG products…………………………………………………………………………… 3‐9
3.2.2 Exercise/stress testing products………………………………………………………….. 3‐11
3.2.3 Holter monitor ECG products ……………………………………………………………… 3‐12
3.2.4 External event loop recorder products…………………………………………………. 3‐13
3.2.5 Implantable loop recorder/insertable cardiac monitor products …………….. 3‐14
3.3 Market forecast……………………………………………………………………………………………….. 3‐15
3.3.1 Market forecast: US …………………………………………………………………………… 3‐15
3.3.2 Market forecast: five major EU markets……………………………………………….. 3‐30
3.3.3 Market forecast: Japan ………………………………………………………………………. 3‐42
3.3.4 Market forecast: RoW………………………………………………………………………… 3‐52
3.4 Bibliography ……………………………………………………………………………………………………. 3‐65

Exhibit 3‐1: Diagnostic ECG products, global market forecast ($m), 2017‐22……………………………… 3‐2
Exhibit 3‐2: Global diagnostic ECG equipment product sales, by product segment, combined  market forecast ($m), 2017‐22 …………………………………………………………………………… 3‐3
Exhibit 3‐3: Global diagnostic ECG products market, share by country/region, 2017 ………………….. 3‐4
Exhibit 3‐4: Global diagnostic ECG products market ($m), share by country/region, 2017‐22………. 3‐4
Exhibit 3‐5: Market drivers and limiters for the ECG products segment…………………………………….. 3‐7
Exhibit 3‐6: Types of diagnostic ECG products by use and features…………………………………………… 3‐8
Exhibit 3‐7: Global diagnostic resting products market, share by supplier, 2017 ………………………. 3‐11
Exhibit 3‐8: Global diagnostic ECG exercise/stress testing products market, share  by supplier, 2017 …………………………………………………………………………………………….. 3‐12
Exhibit 3‐9: Global Holter monitor products market, share by supplier, 2017 ………………………….. 3‐13
Exhibit 3‐10: Global event loop recorder market, share by supplier, 2017……………………………….. 3‐14
Exhibit 3‐11: Global implantable loop recorder products market, share by supplier, 2017 ………… 3‐15
Exhibit 3‐12: US diagnostic ECG product sales, combined market forecast ($m), by product  segment, 2017‐22………………………………………………………………………………………….. 3‐17
Exhibit 3‐13: US resting ECG products, market forecast, 2017‐22 …………………………………………… 3‐18
Exhibit 3‐14: Selected medical association guidelines for exercise/stress testing……………………… 3‐20
Exhibit 3‐15: US exercise/stress testing products, market forecast, 2017‐22……………………………. 3‐21
Exhibit 3‐16: US resting and exercise/stress ECG products market, share by supplier, 2017………. 3‐22
Exhibit 3‐17: US Holter monitor products, market forecast, 2017‐22………………………………………. 3‐24
Exhibit 3‐18: US event loop recorders, market forecast, 2017‐22 …………………………………………… 3‐25
Exhibit 3‐19: US Holter monitor and event loop recorder products market, share  by supplier, 2017 …………………………………………………………………………………………… 3‐26
Exhibit 3‐20: US end‐users for selected diagnostic ECG products, combined market  forecast ($m), 2017‐22. ………………………………………………………………………………….. 3‐27
Exhibit 3‐21: US implantable loop recorders, market forecast, 2017‐22 ………………………………….. 3‐29
Exhibit 3‐22: US implantable loop recorder products market, share by supplier, 2017 ……………… 3‐30
Exhibit 3‐23: 5EU diagnostic ECG product sales, combined market forecast ($m), by product segment, 2017‐22………………………………………………………………………………………….. 3‐32
Exhibit 3‐24: 5EU resting ECG products, market forecast, 2017‐22 …………………………………………. 3‐33
Exhibit 3‐25: 5EU exercise/stress testing products, market forecast, 2017‐22………………………….. 3‐34
Exhibit 3‐26: 5EU resting ECG and stress testing markets, share by supplier, 2017 …………………… 3‐35
Exhibit 3‐27: 5EU Holter monitor products, market forecast, 2017‐22…………………………………….. 3‐36
Exhibit 3‐28: 5EU event loop recorders, market forecast, 2017‐22 …………………………………………. 3‐37
Exhibit 3‐29: 5EU Holter monitor and event loop recorder products market, share  by supplier, 2017 …………………………………………………………………………………………… 3‐38
Exhibit 3‐30: 5EU end‐users for selected diagnostic ECG products, combined market  forecast ($m), 2017‐22. ………………………………………………………………………………….. 3‐39
Exhibit 3‐31: 5EU implantable loop recorders, market forecast, 2017‐22 ………………………………… 3‐41
Exhibit 3‐32: 5EU implantable loop recorders markets, share by supplier, 2017 ………………………. 3‐41
Exhibit 3‐33: Japan diagnostic ECG product sales, combined market forecast ($m), by product segment, 2017‐22………………………………………………………………………………………….. 3‐43
Exhibit 3‐34: Japan resting ECG products, market forecast, 2017‐22 ………………………………………. 3‐44
Exhibit 3‐35: Japan exercise/stress testing products, market forecast, 2017‐22……………………….. 3‐45
Exhibit 3‐36: Exercise/stress testing procedure volumes in Japan, 2012‐16……………………………… 3‐46
Exhibit 3‐37: Japan resting and exercise/stress testing products market, share  by supplier, 2017 …………………………………………………………………………………………… 3‐46
Exhibit 3‐38: Japan Holter monitor products, market forecast, 2017‐22………………………………….. 3‐47
Exhibit 3‐39: Japan event loop recorders, market forecast, 2017‐22 ………………………………………. 3‐48
Exhibit 3‐40: Japan Holter monitor and event loop recorder products market, share  by supplier, 2017 …………………………………………………………………………………………… 3‐49
Exhibit 3‐41: Japan end‐users for selected diagnostic ECG products, combined market  forecast ($m), 2017‐22. ………………………………………………………………………………….. 3‐50
Exhibit 3‐42: Japan implantable loop recorders, market forecast, 2017‐22 ……………………………… 3‐51
Exhibit 3‐43: Japan implantable loop recorders market, share by supplier, 2017 ……………………… 3‐52
Exhibit 3‐44: RoW diagnostic ECG product sales, combined market forecast ($m), by product segment, 2017‐22………………………………………………………………………………………….. 3‐54
Exhibit 3‐45: RoW resting ECG products market forecast, 2017‐22…………………………………………. 3‐55
Exhibit 3‐46: RoW exercise/stress testing products, market forecast, 2017‐22 ………………………… 3‐56
Exhibit 3‐47: RoW resting and stress exercise/testing market, share by supplier, 2017 …………….. 3‐57
Exhibit 3‐48: RoW Holter monitor products, market forecast, 2017‐22. ………………………………….. 3‐58
Exhibit 3‐49: RoW event loop recorders, market forecast, 2017‐22………………………………………… 3‐59
Exhibit 3‐50: RoW Holter monitor and event loop recorder products market, share  by supplier, 2017 …………………………………………………………………………………………… 3‐60
Exhibit 3‐51: RoW end‐users for selected diagnostic ECG products, combined market  forecast ($m), 2017‐22. ………………………………………………………………………………….. 3‐61
Exhibit 3‐52: RoW implantable loop recorders, market forecast, 2017‐22……………………………….. 3‐63
Exhibit 3‐53: RoW implantable loop recorders market, share by supplier, 2017……………………….. 3‐64
Appendix: Company Listing………………………………………………………………………………………………….. A‐1