Interventional Neurology: Cerebral Aneurysm and Arteriovenous Malformation Systems
Interventional Neurology: Cerebral Aneurysm and Arteriovenous Malformation Systems
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This medical market and technology report provides a comprehensive discussion of the global market for neurointerventional cerebral aneurysm and AVM embolization systems. This market comprises the following product segments: endovascular coils, liquid embolics, stents for stent-assisted coiling, flow diversion and flow disruption systems, and other novel/emerging embolization devices. Markets covered by this analysis comprise the US, Japan, the five major European markets (France, Germany, Italy, Spain, and the UK), and the rest of world (RoW) markets. The forecast range for this report is 2020–25.
Publisher: Meddevicetracker
- Highlights
- Description
- Contents
Executive Summary
This medical market and technology report provides a comprehensive discussion of the global market for neurointerventional cerebral aneurysm and arteriovenous malformation (AVM) embolization systems. This market, as covered by the scope of this analysis, comprises the following product segments: endovascular coils, liquid embolics, stents for stent-assisted coiling, flow diversion and flow disruption systems, and other novel/emerging embolization devices. Markets covered by this analysis comprise the US, Japan, the five major European markets (France, Germany, Italy, Spain, and the UK), and the rest of world (RoW) markets, which includes all other countries.
This report provides the following useful information:
- clinical overview of neurointerventional embolization procedures for
intracranial applications - incidence and prevalence data for cerebral aneurysms and AVMs
- product portfolios offered by leading manufacturers
- top-selling devices, as well as emerging products
- in-depth market and competitive analyses.
Overview
In 2020, embolic coiling procedures represented the largest share of cerebral aneurysm and AVM embolization procedures with a share of about three-quarters, followed by stent-assisted coiling, flow diversion and other novel/emerging embolization, and liquid embolization. In 2020, the combined global market for cerebral aneurysm and AVM embolization systems was estimated at $1.2bn. Market drivers include the aging population, the advancement of screening techniques leading to increased diagnosis, advances in microsurgery, and new product introductions. This medical market and technology report provides a comprehensive discussion of the global market for neurointerventional cerebral aneurysm and AVM embolization systems. This market comprises the following product segments: endovascular coils, liquid embolics, stents for stent-assisted coiling, flow diversion and flow disruption systems, and other novel/emerging embolization devices. Markets covered by this analysis comprise the US, Japan, the five major European markets (France, Germany, Italy, Spain, and the UK), and the rest of world (RoW) markets. The forecast range for this report is 2020–25.
Table of Contents
Executive Summary …………………………………………………………………….. ES-1
i. Embolization systems………………………………………………………………………………………. ES-1
a. Embolic coiling……………………………………………………………………………………. ES-1
b. Liquid embolics…………………………………………………………………………………… ES-2
c. Stent-assisted coiling …………………………………………………………………………… ES-2
d. Flow diversion and other novel/emerging embolic systems……………………….. ES-2
ii. Combined market forecast………………………………………………………………………………. ES-3
a. Market leaders …………………………………………………………………………………… ES-5
iii. Methodology………………………………………………………………………………………………… ES-5
Exhibit ES-1: Cerebral aneurysm and AVM embolization systems, combined market forecast ($m), by region, 2020–25……………………………………. ES-4
1. Clinical Overview ……………………………………………………………………….1-1
1.1 Intracerebral hemorrhage ………………………………………………………………………………..1-3
1.2 Subarachnoid hemorrhage ……………………………………………………………………………….1-3
1.3 Cerebral aneurysm………………………………………………………………………………………….1-4
1.4 Arteriovenous malformations……………………………………………………………………………1-5
1.5 Repair of cerebral aneurysms and AVMs…………………………………………………………….1-5
1.5.1 Surgical clipping………………………………………………………………………………..1-6
1.5.2 Endovascular embolization …………………………………………………………………1-6
1.5.3 Stent-assisted coiling …………………………………………………………………………1-9
1.5.4 Flow diversion and other endovascular treatment options……………………….1-9
1.6 Bibliography…………………………………………………………………………………………………1-11
Exhibit 1-1: Clinical features and characteristics of hemorrhagic stroke…………………………1-2
Exhibit 1-2: Global incidence and prevalence of hemorrhagic stroke (millions), 1990 and 2013 …………………………………………………………………………………………1-3
Exhibit 1-3: Illustration of an embolic coil procedure for cerebral aneurysm treatment……1-7
Exhibit 1-4: Illustration of an endovascular embolization procedure for AVM treatment….1-8
2. Neuroendovascular Embolization Products……………………………………..2-1
2.1 Microcoil embolization products……………………………………………………………………….2-2
2.2 Liquid embolics………………………………………………………………………………………………2-5
2.3 Stent products for wide-neck aneurysms…………………………………………………………….2-7
2.3.1 Laser-cut stents ………………………………………………………………………………..2-8
2.3.2 Braided stents…………………………………………………………………………………..2-8
2.4 Flow diversion devices …………………………………………………………………………………..2-10
2.5 Flow disruption and other novel/emerging aneurysm embolization devices……………2-12
2.5.1 Endosaccular flow disruptors…………………………………………………………….2-13
2.5.2 Neck-bridging flow disruptors……………………………………………………………2-14
2.5.3 Temporary coil assist devices…………………………………………………………….2-15
2.6 Current clinical trials ……………………………………………………………………………………..2-17
2.7 Bibliography…………………………………………………………………………………………………2-19
Exhibit 2-1: Advantages and disadvantages of cerebral aneurysm clipping versus coiling procedures…………………………………………………………………………………….2-1
Exhibit 2-2: Selected neuroendovascular aneurysm microcoils, 2021 ……………………………2-4
Exhibit 2-3: Selected liquid embolic products, 2021……………………………………………………2-6
Exhibit 2-4: Liquid embolic products in development, 2021…………………………………………2-7
Exhibit 2-5: Selected neuroendovascular stents for wide-neck aneurysms, 2021…………….2-9
Exhibit 2-6: Selected flow diversion devices, 2021……………………………………………………2-12
Exhibit 2-7: Selected flow disruption and other novel embolic systems, 2021 ………………2-16
Exhibit 2-8: Selected clinical trials of neuroendovascular embolic systems for cerebral aneurysms and AVMs, 2021………………………………………………………….2-17
3. Cerebral Aneurysm and Arteriovenous Malformation Embolization Systems Market ……………………………………………………………………………3-1
3.1 Combined market forecast……………………………………………………………………………….3-1
3.1.1 Drivers and limiters……………………………………………………………………………3-6
3.2 Combined procedure volumes forecast………………………………………………………………3-7
3.3 Combined competitive analysis……………………………………………………………………….3-10
3.4 Embolic coiling ……………………………………………………………………………………………..3-12
3.4.1 Procedure volumes forecast ……………………………………………………………..3-13
3.4.2 Market forecast………………………………………………………………………………3-15
3.4.3 Competitive analysis………………………………………………………………………..3-18
3.5 Liquid embolics…………………………………………………………………………………………….3-20
3.5.1 Procedure volumes forecast ……………………………………………………………..3-21
3.5.2 Market forecast………………………………………………………………………………3-23
3.5.3 Competitive analysis………………………………………………………………………..3-26
3.6 Stent-assisted coiling……………………………………………………………………………………..3-27
3.6.1 Procedure volumes forecast ……………………………………………………………..3-27
3.6.2 Market forecast………………………………………………………………………………3-30
3.6.3 Competitive analysis………………………………………………………………………..3-33
3.7 Flow diversion and other novel/emerging systems……………………………………………..3-34
3.7.1 Procedure volumes forecast ……………………………………………………………..3-34
3.7.2 Market forecast………………………………………………………………………………3-36
3.7.3 Competitive analysis………………………………………………………………………..3-39
3.8 Bibliography…………………………………………………………………………………………………3-42
Exhibit 3-1: Cerebral aneurysm and AVM embolization systems, combined market forecast ($m), by region, 2020–25………………………………………3-3
Exhibit 3-2: Cerebral aneurysm and AVM embolization systems market, share by country/region, 2020…………………………………………………………………….3-4
Exhibit 3-3: Cerebral aneurysm and AVM embolization systems, combined market forecast ($m), by product segment, 2020–25 ……………………….3-5
Exhibit 3-4: Neuroendovascular embolization, procedure volumes forecast, by type, 2020–25………………………………………………………………………………………3-8
Exhibit 3-5: Neuroendovascular embolization, procedure volumes forecast, by country/region, 2020–25 ……………………………………………………………………….3-9
Exhibit 3-6: Neuroendovascular embolization procedures, share by country/region, 2020…………………………………………………………………..3-10
Exhibit 3-7: Cerebral aneurysm and AVM embolization systems market, share by supplier, 2020 ……………………………………………………………………………3-12
Exhibit 3-8: Embolic coiling, procedure volumes forecast, by region, 2020–25 ……………..3-14
Exhibit 3-9: Embolic coiling procedures, share by country/region, 2020 ………………………3-15
Exhibit 3-10: Neuroendovascular coiling systems, market forecast ($m), 2020–25 ………..3-16
Exhibit 3-11: Neuroendovascular coiling systems market, share by country/region, 2020…………………………………………………………………..3-18
Exhibit 3-12: Neuroendovascular coiling systems market, share by supplier, 2020 ………..3-20
Exhibit 3-13: Neuroendovascular liquid embolization, procedure volumes forecast, by country/region, 2020–25 ……………………………………………………………………..3-22
Exhibit 3-14: Neuroendovascular liquid embolization procedures, share by country/region, 2020…………………………………………………………………..3-23
Exhibit 3-15: Neuroendovascular liquid embolics, market forecast ($m), by country/region, 2020–25 ……………………………………………………………………..3-24
Exhibit 3-16: Neuroendovascular liquid embolics market, share by country/region, 2020…………………………………………………………………..3-26
Exhibit 3-17: Neuroendovascular liquid embolics market, share by supplier, 2020 ………..3-27
Exhibit 3-18: Neuroendovascular stent-assisted coiling, procedure volumes forecast, by country/region, 2020–25 ……………………………………………………………………..3-29
Exhibit 3-19: Neuroendovascular stent-assisted coiling procedures, share by country/region, 2020…………………………………………………………………..3-30
Exhibit 3-20: Intracranial coil-containment stents, market forecast ($m), by country/region, 2020–25 ……………………………………………………………………..3-31
Exhibit 3-21: Intracranial coil-containment stents market, share by country/region, 2020…………………………………………………………………..3-33
Exhibit 3-22: Intracranial coil-containment stents market, share by supplier, 2020 ……….3-34
Exhibit 3-23: Flow diversion and other novel/emerging embolization, procedure volumes forecast, by country/region, 2020–25……………………………..3-35
Exhibit 3-24: Flow diversion and other novel/emerging embolization procedures, share by country/region, 2020…………………………………………………………………..3-36
Exhibit 3-25: Flow diversion and other novel/emerging embolization systems, market forecast ($m), by country/region, 2020–25……………………………………….3-37
Exhibit 3-26: Flow diversion and other novel/emerging embolization products market, share by country/region, 2020…………………………………………………………………..3-39
Exhibit 3-27: Flow diversion and other novel/emerging embolization products market, share by supplier, 2020 ……………………………………………………………………………3-41
Appendix: Company Listing……………………………………………………………. A-1
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