Drug Overview
Iomab-B is a radioimmunotherapy comprised of the monoclonal antibody BC8 coupled with the radioisotope Iodine-131. Iomab-B is designed to deliver targeted payloads to cells that express CD45, a pan-leukemic antigen expressed on white blood cells and stem cells. Once attached to target cells, the radioisotope emits energy that destroys cancer cells and bone marrow, thus conditioning the patient prior to HSCT.
TABLE OF CONTENTS
4 PRODUCT PROFILES
4 Iomab-B : Acute myeloid leukemia (AML)
LIST OF FIGURES
7 Figure 1: Iomab-B for acute myeloid leukemia – SWOT analysis
8 Figure 2: Datamonitor Healthcare’s drug assessment summary of Iomab-B for acute myeloid leukemia
9 Figure 3: Datamonitor Healthcare’s drug assessment summary of Iomab-B for acute myeloid leukemia
LIST OF TABLES
5 Table 1: Iomab-B drug profile
6 Table 2: Iomab-B late-phase trials in acute myeloid leukemia