Iomab-B is a radioimmunotherapy comprised of the monoclonal antibody BC8 coupled with the radioisotope Iodine-131. Iomab-B is designed to deliver targeted payloads to cells that express CD45, a pan-leukemic antigen expressed on white blood cells and stem cells. Once attached to target cells, the radioisotope emits energy that destroys cancer cells and bone marrow, thus conditioning the patient prior to HSCT.
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