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This Market Spotlight report covers the Dry Eye Disease market, comprising key marketed and pipeline drugs, clinical trials, recent events and analyst opinion, upcoming and regulatory events, probability of success, a 10-year disease prevalence forecast, and licensing and acquisition deals, as well as presenting drug-specific revenue forecasts.
This Market Spotlight report covers the Dry Eye Disease market, comprising key marketed and pipeline drugs, clinical trials, recent events and analyst opinion, upcoming and regulatory events, probability of success, a 10-year disease prevalence forecast, and licensing and acquisition deals, as well as presenting drug-specific revenue forecasts.
Key Takeaways
CONTENTS
6 OVERVIEW
7 KEY TAKEAWAYS
8 DISEASE BACKGROUND
8 Definition
8 Patient segmentation
9 Symptoms
9 Risk factors
9 Diagnosis
10 TREATMENT
10 Ocular lubricants
10 Prescription drugs
11 Eyelid hygiene
12 Surgical treatment
13 EPIDEMIOLOGY
17 MARKETED DRUGS
20 PIPELINE DRUGS
27 RECENT EVENTS AND ANALYST OPINION
27 OCS-02 for Dry Eye (July 6, 2022)
28 Reproxalap for Dry Eye (June 8, 2022)
30 ST-100 for Dry Eye (January 3, 2022)
31 CyclASol for Dry Eye (December 21, 2021)
33 OTX-DED for Dry Eye (December 6, 2021)
34 OTX-CSI for Dry Eye (October 22, 2021)
36 NovaTears for Dry Eye (September 30, 2021)
37 AR-15512 for Dry Eye (September 15, 2021)
39 NovaTears for Dry Eye (April 13, 2021)
42 KEY UPCOMING EVENTS
43 KEY REGULATORY EVENTS
43 Novaliq Platform Supports Two Dry Eye NDAs
43 Théa Invests Further In UK With Latest Dry Eye Launch
43 Thea Pharmaceuticals Adds Reusable Eye Compress To UK Blepha Range
44 Viatris Readies Restasis Launch – So Where Are The Others?
44 Oyster Point Prepares Major Push For New Dry Eye Drug
45 PROBABILITY OF SUCCESS
46 LICENSING AND ASSET ACQUISITION DEALS
46 Alcon Buys Aerie, Reaffirming Commitment To Pharma Space
46 Alcon Pays $60m Up Front For Two Kala Eye Care Therapies
46 Acquisition By HLB Group To Speed Up GtreeBNT’s Programs
48 REVENUE OPPORTUNITY
49 CLINICAL TRIAL LANDSCAPE
50 Sponsors by status
51 Sponsors by phase
52 Recent events
55 BIBLIOGRAPHY
56 APPENDIX
LIST OF FIGURES
16 Figure 1: Trends in prevalent cases of dry eye disease, 2021–30
20 Figure 2: Overview of pipeline drugs for dry eye disease in the US
20 Figure 3: Pipeline drugs for dry eye disease, by company
21 Figure 4: Pipeline drugs for dry eye disease, by drug type
21 Figure 5: Pipeline drugs for dry eye disease, by classification
28 Figure 6: OCS-02 for Dry Eye (July 6, 2022): Phase II – 2202
30 Figure 7: Reproxalap for Dry Eye (June 8, 2022): Phase III – TRANQUILITY 2
33 Figure 8: CyclASol for Dry Eye (December 21, 2021): Phase III – ESSENCE-2
34 Figure 9: OTX-DED for Dry Eye (December 6, 2021): Phase II – OTX-DED-2020-201
36 Figure 10: OTX-CSI for Dry Eye (October 22, 2021): Phase II – w/Vehicle
37 Figure 11: NovaTears for Dry Eye (September 30, 2021): Phase III – MOJAVE
39 Figure 12: AR-15512 for Dry Eye (September 15, 2021): Phase IIb – COMET-1
41 Figure 13: NovaTears for Dry Eye (April 13, 2021): Phase III – GOBI
42 Figure 14: Key upcoming events in dry eye disease
45 Figure 15: Probability of success in the dry eye pipeline
49 Figure 16: Clinical trials in dry eye disease
49 Figure 17: Top 10 drugs for clinical trials in dry eye disease
50 Figure 18: Top 10 companies for clinical trials in dry eye disease
50 Figure 19: Trial locations in dry eye disease
51 Figure 20: Dry eye disease trials status
52 Figure 21: Dry eye disease trials sponsors, by phase
LIST OF TABLES
14 Table 1: Prevalent cases of dry eye disease, 2021–30
18 Table 2: Marketed drugs for dry eye disease
22 Table 3: Pipeline drugs for dry eye disease in the US
27 Table 4: OCS-02 for Dry Eye (July 6, 2022)
29 Table 5: Reproxalap for Dry Eye (June 8, 2022)
31 Table 6: ST-100 for Dry Eye (January 3, 2022)
32 Table 7: CyclASol for Dry Eye (December 21, 2021)
33 Table 8: OTX-DED for Dry Eye (December 6, 2021)
35 Table 9: OTX-CSI for Dry Eye (October 22, 2021)
36 Table 10: NovaTears for Dry Eye (September 30, 2021)
38 Table 11: AR-15512 for Dry Eye (September 15, 2021)
40 Table 12: NovaTears for Dry Eye (April 13, 2021)
48 Table 13: Historical global sales, by drug ($m), 2017–21
48 Table 14: Forecasted global sales, by drug ($m), 2022–26
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