Meningitis is an infection of the meninges, the membranes surrounding the brain and spinal cord. It can be caused by a number of different viral and bacterial pathogens including Haemophilus influenzae b (Hib) and Streptococcus pneumoniae. However, in the US, Neisseria meningitidis is the most common cause of bacterial meningitis in infants and young children, as well as one of the most important causes in adults. There are 13 known serotypes of meningococcal disease, of which five (A, B, C, Y, and W-135) account for 90% of the global disease burden.
- Continued uptake of MenB vaccines and GlaxoSmithKline’s pentavalent vaccine launch from 2021 will drive market growth.
- Cost-effectiveness concerns and scarcity of real-world effectiveness data are key resistors of uptake for MenB vaccines.
- Pipeline vaccines with broader serotype protection and novel approaches are positioned to replace marketed products.