$4,750.00
This medical market and technology report provides a comprehensive discussion of the global market for neurointerventional cerebral aneurysm and arteriovenous malformation (AVM) embolization systems.
This report provides the following useful information:
Despite the impact of COVID-19 on most medical device markets, global sales of mechanical thrombectomy devices for the emergency treatment of acute ischemic stroke (AIS)—which includes both stent retrievers and aspiration devices and associated products—is expected to increase at a healthy CAGR of approximately 5.7%, from nearly $677m in 2019 to an estimated $894m in 2024.
Stent retrievers contribute approximately 60% of sales; however, aspiration devices remain a valid option and are also exhibiting solid growth, complementing stent retrievers in ensuring complete clot removal.
Next-generation stent retriever devices include innovative designs that improve clot capture and allow for more atraumatic clot removal from selected vessels in the brain (large vessel occlusion/LVO of the internal carotid artery or proximal middle cerebral artery).
Solid clinical evidence for mechanical thrombectomy, particularly stent retrievers, has been established supporting superior clinical outcomes and use as a supplemental therapy to the first line of thrombolytic medication therapy—intravenous recombinant tissue plasminogen activator (IV r-tPA)—when tPA fails or is not an option to re-establish blood flow in the brain. The goal of more comprehensive medication plus mechanical thrombectomy therapy is to rescue cells in the penumbra before further irreversible ischemic injury occurs that often results in severe disability or death.
Key competitors in the mechanical thrombectomy devices market include five major medical devices companies and one startup: Medtronic, Penumbra, Stryker, Cerenovus/Johnson & Johnson, MicroVention/Terumo, and Rapid Medical.
This medical device market and technology report provides:
Markets covered by this analysis include the US, Japan, the five major European markets (France, Germany, Italy, Spain, and the UK), and the Rest of World (RoW) markets, which includes all other countries. Market forecasts are for the 2019-24 time period.
Executive Summary……………………………………………………………………………………………….. ES-1
i. Mechanical thrombectomy devices market …………………………………………………………….ES-1
ii. Market leaders……………………………………………………………………………………………………ES-4
iii. Methodology……………………………………………………………………………………………………..ES-5
Exhibit ES-1: Combined mechanical thrombectomy devices market, stent retrievers and aspiration devices, forecast sales by segment ($m), 2019–24 …………………… ES-3
Exhibit ES-2: Combined mechanical thrombectomy devices market, stent retrievers and aspiration devices, estimated global share by supplier, 2019……………………. ES-4
1. Clinical Overview…………………………………………………………………………………………………. 1-1
1.1 Stroke statistics…………………………………………………………………………………………………. 1-1
1.2 Types of stroke………………………………………………………………………………………………….. 1-3
1.3 Stroke symptoms ………………………………………………………………………………………………. 1-8
1.4 Stroke risk factors ……………………………………………………………………………………………… 1-8
1.5 The effects of stroke ………………………………………………………………………………………….. 1-9
1.6 Diagnostic tests for stroke ………………………………………………………………………………….. 1-9
1.7 Treatment for ischemic stroke…………………………………………………………………………… 1-10
1.8 Clinical data supporting use of mechanical thrombectomy …………………………………… 1-12
1.9 Bibliography ……………………………………………………………………………………………………. 1-15
Exhibit 1-1: Diagram of an ischemic stroke due to atherosclerosis ………………………………. 1-4
Exhibit 1-2: Diagram of an ischemic stroke in the middle cerebral artery territory …………. 1-5
Exhibit 1-3: Diagram of a hemorrhagic stroke due to a cerebral aneurysm……………………. 1-7
2. Mechanical Thrombectomy Devices for Acute Ischemic Stroke ……………………………………. 2-1
2.1 Stent retrievers…………………………………………………………………………………………………. 2-1
2.1.1 Cerenovus/Johnson & Johnson……………………………………………………………… 2-6
2.1.2 Medtronic ………………………………………………………………………………………… 2-10
2.1.3 MicroVention/Terumo……………………………………………………………………….. 2-18
2.1.4 Rapid Medical …………………………………………………………………………………… 2-19
2.1.5 Stryker……………………………………………………………………………………………… 2-21
2.2 Aspiration systems…………………………………………………………………………………………… 2-26
2.2.1 Medtronic ………………………………………………………………………………………… 2-26
2.2.2 MicroVention/Terumo……………………………………………………………………….. 2-28
2.2.3 Penumbra…………………………………………………………………………………………. 2-29
2.3 Bibliography ……………………………………………………………………………………………………. 2-32
Exhibit 2-1: Selected newly FDA approved stent retrievers, 2019–20 …………………………… 2-2
Exhibit 2-2: Selected leading stent retrievers, 2020…………………………………………………… 2-3
Exhibit 2-3: EmboTrap II Revascularization Device ……………………………………………………. 2-7
Exhibit 2-4: EmboTrap III Revascularization Device and Cerenovus Stroke Solutions suite……………………………………………………………………………………. 2-8
Exhibit 2-5: Solitaire X Revascularization Device …………………………………………………….. 2-11
Exhibit 2-6: Viz.ai’s new AI stroke detection smartphone-based technology used with Medtronic’s Solitaire stent retriever……………………………………………… 2-17
Exhibit 2-7: The ERIC Retrieval Device…………………………………………………………………… 2-18
Exhibit 2-8: Tigertriever XL adjustable clot retriever removing a blood clot in the brain … 2-20
Exhibit 2-9: Trevo XP ProVue Stentriever ………………………………………………………………. 2-22
Exhibit 2-10: Riptide Aspiration System ………………………………………………………………….. 2-27
Exhibit 2-11: SOFIA Plus Aspiration Catheter………………………………………………………………. 28
Exhibit 2-12: Penumbra System ……………………………………………………………………………….. 30
3. Market Analysis…………………………………………………………………………………………………… 3-1
3.1 Stent retrievers market………………………………………………………………………………………. 3-1
3.1.1 Market forecast: global………………………………………………………………………… 3-2
3.1.2 Market forecast: by region …………………………………………………………………… 3-4
3.1.3 Market share: global……………………………………………………………………………. 3-6
3.1.4 Market share: by region……………………………………………………………………….. 3-8
3.2 Aspiration devices market ………………………………………………………………………………… 3-10
3.2.1 Market forecast: global………………………………………………………………………. 3-10
3.2.2 Market forecast: by region …………………………………………………………………. 3-12
3.2.3 Market share: global………………………………………………………………………….. 3-14
3.2.4 Market share: by region……………………………………………………………………… 3-15
3.3 Combined market ……………………………………………………………………………………………. 3-16
3.3.1 Combined market forecast …………………………………………………………………. 3-16
3.3.2 Combined market share …………………………………………………………………….. 3-18
3.3.3 Market drivers and limiters ………………………………………………………………… 3-19
3.3.4 Estimated combined procedure volumes……………………………………………… 3-20
3.4 Corporate profiles……………………………………………………………………………………………. 3-22
3.4.1 Johnson & Johnson ……………………………………………………………………………. 3-22
3.4.2 Medtronic ………………………………………………………………………………………… 3-24
3.4.3 MicroVention/Terumo Corporation …………………………………………………….. 3-33
3.4.4 Penumbra…………………………………………………………………………………………. 3-35
3.4.5 Stryker……………………………………………………………………………………………… 3-39
3.5 Bibliography ……………………………………………………………………………………………………. 3-42
Exhibit 3-1: Stent retrievers, global market forecast ($m), 2019–24 …………………………….. 3-3
Exhibit 3-2: Stent retrievers market, estimated sales and share of revenues by region, 2019…………………………………………………………………………………… 3-4
Exhibit 3-3: Stent retrievers market, forecast sales by region ($m), 2019–24…………………. 3-5
Exhibit 3-4: Stent retrievers market, estimated global share by supplier, 2019………………. 3-7
Exhibit 3-5: Stent retrievers market, estimated share by supplier and region, 2019 ……….. 3-9
Exhibit 3-6: Aspiration devices, global market forecast ($m), 2019–24 ……………………….. 3-11
Exhibit 3-7: Aspiration devices market, estimated sales and share of revenues by region, 2019…………………………………………………………………………………. 3-12
Exhibit 3-8: Aspiration devices market, forecast sales by region ($m), 2019–24 …………… 3-13
Exhibit 3-9: Aspiration devices market, estimated global share by supplier, 2019 ………… 3-14
Exhibit 3-10: Aspiration devices market, estimated share by supplier and region, 2019 ….. 3-15
Exhibit 3-11: Combined mechanical thrombectomy devices market, stent retrievers and aspiration devices, forecast sales by segment ($m), 2019–24……………… 3-17
Exhibit 3-12: Combined mechanical thrombectomy devices market, stent retrievers and aspiration devices, estimated global share by supplier, 2019 ……………… 3-18
Exhibit 3-13: Mechanical thrombectomy procedure volumes forecast, by segment and region, 2019–24………………………………………………………………………….. 3-21
Exhibit 3-14: Johnson & Johnson, revenues by segment, FY2018–19 ……………………………. 3-23
Exhibit 3-15: Medtronic, revenues by segment, FY2019–20………………………………………… 3-32
Exhibit 3-16: Terumo, revenues by segment, FY2019–20……………………………………………. 3-34
Exhibit 3-17: Penumbra, revenues by segment, FY2018–19………………………………………… 3-38
Exhibit 3-18: Stryker, revenues by segment, FY2018–19…………………………………………….. 3-41
Appendix A: company listing
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