Pfizer’s PF-06482077 is a 20-valent pneumococcal conjugate vaccine, which is currently in Phase II development in the US and EU. PF-06482077 contains the 13 serotypes included in Prevnar 13 (4, 6B, 9V, 14, 18C, 19F, 23F, 1, 3, 5, 6A, 7F, and 19A), as well as seven additional serotypes.
The broad serotype coverage of PF-06482077 (20-valent pneumococcal conjugate vaccine; Pfizer) gives it significant market potential,
but it needs to demonstrate at least non-inferior immunogenicity to Prevnar 13 (13-valent pneumococcal conjugate vaccine; Pfizer) in
Phase II studies.
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