TABLE OF CONTENTS

Executive Summary…………………………………………………………………………………………………………….ES-1
i. Global market for robotically assisted surgical systems…………………………………………………..ES-1
a. Selected market drivers and limiters………………………………………………………….ES-3
b. Market leaders………………………………………………………………………………………..ES-4
ii. Methodology ……………………………………………………………………………………………………………ES-6

Exhibit ES-1: Robotically assisted surgical devices, global market forecast ($m), by revenue segment, 2018–23 ………………………………………………………………………….ES-2
Exhibit ES-2: Robotically assisted surgical devices market, share by country/region, 2018………….ES-3
Exhibit ES-3: Robotically assisted surgical devices market, global share by supplier, 2018…………..ES-5

1. Robotically Assisted Surgery ………………………………………………………….1-1
1.1 Robotically assisted procedures………………………………………………………………………….. 1-2
1.2 Clinical applications…………………………………………………………………………………………… 1-4
1.2.1 Brain surgery ……………………………………………………………………………………… 1-4
1.2.2 Cardiothoracic surgery………………………………………………………………………… 1-4
1.2.3 General surgery………………………………………………………………………………….. 1-5
1.2.4 Gynecologic……………………………………………………………………………………….. 1-6
1.2.5 Head and neck……………………………………………………………………………………. 1-7
1.2.6 Orthopedic and spine………………………………………………………………………….. 1-7
1.2.7 Urologic…………………………………………………………………………………………….. 1-7
1.3 FDA adverse event reports ………………………………………………………………………………… 1-8
1.4 Bibliography …………………………………………………………………………………………………….. 1-9

Exhibit 1-1: Advantages and disadvantages of robotically assisted surgery ………………………………. 1-1
Exhibit 1-2: Intuitive Surgical’s da Vinci surgical system procedure volumes, by clinical application and geographic area, 2018 …………………………………………………. 1-3

2. Robotically Assisted Surgical Devices ………………………………………………2-1
2.1 Robotic systems by clinical application………………………………………………………………… 2-1
2.1.1 Bronchoscopy…………………………………………………………………………………… 2-10
2.1.2 Cardiovascular………………………………………………………………………………….. 2-11
2.1.3 General surgery………………………………………………………………………………… 2-12
2.1.4 Gynecology and urology ……………………………………………………………………. 2-13
2.1.5 Hair transplant …………………………………………………………………………………. 2-13
2.1.6 Head and neck………………………………………………………………………………….. 2-13
2.1.7 Neurovascular………………………………………………………………………………….. 2-13
2.1.8 Stereotactic brain procedures ……………………………………………………………. 2-14
2.1.9 Spine and orthopedic………………………………………………………………………… 2-14
2.1.10 Organ transplant…………………………………………………………………………….. 2-15
2.1.11 Peripheral vascular………………………………………………………………………….. 2-15
2.1.12 Radiology……………………………………………………………………………………….. 2-15
2.1.13 Thoracic…………………………………………………………………………………………. 2-16
2.2 Emerging products………………………………………………………………………………………….. 2-16
2.3 Instruments and holders………………………………………………………………………………….. 2-21
2.4 Bibliography …………………………………………………………………………………………………… 2-26

Exhibit 2-1: Intuitive Surgical’s robotically assisted surgical systems, instruments, and accessories, 2019……………………………………………………………………………………….. 2-2
Exhibit 2-2: Intuitive Surgical’s da Vinci S surgical system……………………………………………………….. 2-3
Exhibit 2-3: Selected robotically assisted surgery and diagnostic devices, 2019 ………………………… 2-4
Exhibit 2-4: Auris Health’s Monarch platform ……………………………………………………………………… 2-10
Exhibit 2-5: Medtronic’s Hugo system………………………………………………………………………………… 2-18
Exhibit 2-6: Selected emerging robotically assisted surgery devices, 2019………………………………. 2-19
Exhibit 2-7: Emerging robotic platform for ophthalmology applications, 2019 ………………………… 2-21
Exhibit 2-8: Selected roboticized instruments/holders, 2019 ………………………………………………… 2-24

3. Market for Robotically Assisted Surgery Systems………………………………3-1
3.1 Global market forecast ……………………………………………………………………………………… 3-1
3.1.1 Market forecast: US ………………………………………………………………………….. 3-13
3.1.2 Outside the US …………………………………………………………………………………. 3-16
3.1.3 Market forecast: five major EU markets………………………………………………. 3-16
3.1.4 Market forecast: Japan ……………………………………………………………………… 3-18
3.1.5 Market forecast: rest of world……………………………………………………………. 3-20
3.1.6 Competitive analysis…………………………………………………………………………. 3-22
3.2 Bibliography …………………………………………………………………………………………………… 3-35

Exhibit 3-1: Robotically assisted surgical devices, global market forecast ($m), by revenue segment, 2018–23……………………………………………………………………………. 3-2
Exhibit 3-2: Robotically assisted surgical devices market, share by country/region, 2018 …………… 3-3
Exhibit 3-3: Robotically assisted surgical devices, market forecast ($m), by country/region, 2018–23………………………………………………………………………………………………………….. 3-4
Exhibit 3-4: Average sales prices of selected robotically assisted surgical devices, 2019 …………….. 3-8
Exhibit 3-5: Robotically assisted surgical devices, US market forecast ($m), 2018–23………………. 3-13
Exhibit 3-6: Robotically assisted surgical devices, five major EU markets forecast ($m), 2018–23………………………………………………………………………………………………………… 3-17
Exhibit 3-7: Robotically assisted surgical devices, Japan market forecast ($m), 2018–23 ………….. 3-18
Exhibit 3-8: Robotically assisted surgical devices market forecast, rest of the world ($m), 2018–23………………………………………………………………………………………………………… 3-20
Exhibit 3-9: Robotically assisted surgical devices market, global share by supplier, 2018………….. 3-23
Exhibit 3-10: Robotically assisted surgical devices market, US share by supplier, 2018……………… 3-30
Exhibit 3-11: Robotically assisted surgical devices market, five major EU markets share by supplier, 2018…………………………………………………………………………………… 3-31
Exhibit 3-12: Robotically assisted surgical devices market, Japan share by supplier, 2018 ………… 3-32
Exhibit 3-13: Robotically assisted surgical devices market, RoW share by supplier, 2018………….. 3-33
Exhibit 3-14: Intuitive Surgical, 2018 revenue ……………………………………………………………………… 3-34

APPENDIX: COMPANY LISTING……………………………………………………………………………………………………..A-1