$4,750.00
Sales of spinal motion preservation devices totaled $1.7bn in 2019, with sales expected to climb at a CAGR of 2.0% during 2019-2024.
Executive Summary
This medical market and technology report provides a comprehensive discussion of spinal motion preservation systems. These devices are used to treat pathologies similar to those addressed by spinal fusion; however, unlike spinal fusion, spinal motion preservation devices act to preserve the natural motion of the spine. This market consists of:
Markets covered by this analysis include the US, Japan, the five major European markets (France, Germany, Italy, Spain, and the UK), and the Rest of World (RoW), which includes all other countries.
This report provides the following useful information:
This new report from Meddevicetracker includes an analysis of products, current/forecast markets, competitors, and opportunities in the global market for spinal motion preservation devices. Market forecasts and analyses are provided for artificial cervical discs, artificial lumbar discs, interspinous process decompression devices, semi-rigid pedicle screw systems, and percutaneous vertebral augmentation systems (for treatment of vertebral compression fractures).
In 2021, the combined global market for spinal motion preservation devices was valued at approximately $1.8bn. Key factors that will drive growth in this market over the forecast period include a desire for patients to avoid spinal fusion and maintain motion in the spine; increasing rates of osteoporosis, osteoarthritis, and degenerative disc disease due to an expanding elderly demographic; and expanded indications and insurance reimbursement for certain product segments. Factors that will limit growth in the market include steep hurdles for regulatory approvals for certain product types and a continuing downward pressure on device prices. Regional markets covered by this analysis include the US, Japan, the five major European markets (France, Germany, Italy, Spain, and the UK), and the rest of world market, which includes all other countries. The forecast range for this report is 2021–26.
This report provides the following useful information:
Table of Contents
Executive Summary…………………………………………………………………………………………………………….ES-1
i. Spinal motion preservation devices market…………………………………………………………………..ES-1
a. Impact of COVID-19 …………………………………………………………………………………ES-3
b. Selected market drivers and limiters………………………………………………………….ES-5
c. Leading competitors…………………………………………………………………………………ES-5
ii. Methodology ……………………………………………………………………………………………………………ES-5
Exhibit ES-1: Spinal motion preservation devices, combined market forecast ($m), by region, 2019—24 ………………………………………………………………………………………..ES-2
Exhibit ES-2: Spinal motion preservation devices, combined market forecast ($m), by product category, 2019—24…………………………………………………………………………ES-4
1. Clinical Overview…………………………………………………………………………………………………………….. 1-1
1.1 Spinal anatomy……………………………………………………………………………………………………….. 1-3
1.2 Selected spinal disorders………………………………………………………………………………………….. 1-6
1.2.1 Disc herniation……………………………………………………………………………………. 1-6
1.2.2 Degenerative disc disease…………………………………………………………………….. 1-7
1.2.3 Abnormal curvature of the Spine ………………………………………………………… 1-10
1.2.4 Spondylolisthesis……………………………………………………………………………….. 1-11
1.2.5 Stenosis……………………………………………………………………………………………. 1-11
1.2.6 Spinal tumors……………………………………………………………………………………. 1-12
1.2.7 Traumatic spinal injuries…………………………………………………………………….. 1-12
1.3 Bibliography………………………………………………………………………………………………………….. 1-14
Exhibit 1-1: Prevalence of lower back pain, per 100,000, Japan and 5 Euro, 2015………………………. 1-1
Exhibit 1-2: Population-based projections for incidence of low back pain, United States…………….. 1-2
Exhibit 1-3: The human spine ………………………………………………………………………………………………. 1-5
Exhibit 1-4: Forecast for prevalent cases of osteoporosis in the US, Japan, and five major European markets, by country, 2019-24 ………………………………………………………………. 1-9
2. Artificial Cervical and Lumbar Discs…………………………………………………………………………………… 2-1
2.1 Fusion vs. nonfusion………………………………………………………………………………………………… 2-1
2.2 Total disc replacement…………………………………………………………………………………………….. 2-1
2.3 Artificial cervical discs………………………………………………………………………………………………. 2-2
2.3.1 Clinical evidence …………………………………………………………………………………. 2-2
2.3.2 Cost effectiveness……………………………………………………………………………….. 2-2
2.3.3 Products/clinical trial results ………………………………………………………………… 2-4
2.3.4 Emerging artificial cervical disc……………………………………………………………. 2-11
2.3.5 Market analysis…………………………………………………………………………………. 2-11
2.3.6 Competitive analysis………………………………………………………………………….. 2-16
2.4 Artificial lumbar discs…………………………………………………………………………………………….. 2-19
2.4.1 Clinical evidence ……………………………………………………………………………….. 2-19
2.4.2 Products/clinical trial results ………………………………………………………………. 2-20
2.4.3 Market analysis…………………………………………………………………………………. 2-24
2.4.4 Competitive analysis………………………………………………………………………….. 2-27
2.5 Artificial discs, combined market forecast………………………………………………………………… 2-30
2.6 Bibliography………………………………………………………………………………………………………….. 2-32
Exhibit 2-1: Cost of Mobi-C artificial cervical disc, UK ……………………………………………………………… 2-3
Exhibit 2-2: Mobi-C artificial cervical disc ……………………………………………………………………………… 2-5
Exhibit 2-3: Prestige LP cervical disc …………………………………………………………………………………….. 2-6
Exhibit 2-4: Selected cervical total disc replacements…………………………………………………………….. 2-9
Exhibit 2-5: Artificial cervical discs, global market forecast ($m), 2019—24…………………………….. 2-12
Exhibit 2-6: Artificial cervical discs market ($m), share by supplier, 2019 ……………………………….. 2-15
Exhibit 2-7: Zimmer Biomet net sales ($m), by product category and region, 2017—19 …………… 2-17
Exhibit 2-8: Medtronic net sales ($m), by product category and region, 2017—19 ………………….. 2-18
Exhibit 2-9: prodisc L artificial lumbar disc ………………………………………………………………………….. 2-22
Exhibit 2-10: Selected lumbar total disc replacements …………………………………………………………. 2-23
Exhibit 2-11: Artificial lumbar discs, global market forecast ($m), 2019—24 …………………………… 2-25
Exhibit 2-12: Artificial lumbar discs market ($m), share by supplier, 2019 ………………………………. 2-28
Exhibit 2-13: B. Braun net sales, by division and region, 2017—19…………………………………………. 2-29
Exhibit 2-14: Artificial discs, combined market forecast ($m), 2019—24 ………………………………… 2-31
3. Dynamic Stabilization Devices ………………………………………………………………………………………….. 3-1
3.1 Interspinous process decompression…………………………………………………………………………. 3-1
3.1.1 Interspinous process decompression products……………………………………….. 3-3
3.1.2 Pedicle screw dynamic stabilization systems ………………………………………… 3-12
3.2 Market forecast…………………………………………………………………………………………………….. 3-17
3.3 Competitive analysis, interspinous process decompression devices…………………………….. 3-24
3.4 Competitive analysis, pedicle screws……………………………………………………………………….. 3-27
3.5 Facet replacement products …………………………………………………………………………………… 3-31
3.6 Bibliography………………………………………………………………………………………………………….. 3-36
Exhibit 3-1: In-Space interspinous spacer………………………………………………………………………………. 3-4
Exhibit 3-2: LimiFlex Paraspinous Tension Band……………………………………………………………………… 3-4
Exhibit 3-3: Renegade interspinous spacer…………………………………………………………………………….. 3-5
Exhibit 3-4: DIAM system…………………………………………………………………………………………………….. 3-5
Exhibit 3-5: coflex interspinous spacer………………………………………………………………………………….. 3-6
Exhibit 3-6: Superion Indirect Decompression System…………………………………………………………….. 3-8
Exhibit 3-7: UniWallis Posterior Dynamic Stabilization System…………………………………………………. 3-9
Exhibit 3-8: Selected interspinous process decompression devices…………………………………………. 3-10
Exhibit 3-9: Zimmer Biomet’s Dynesys dynamic stabilization system ……………………………………… 3-14
Exhibit 3-10: Selected pedicle-screw based semi-rigid/dynamic stabilization systems………………. 3-16
Exhibit 3-11: Dynamic stabilization devices, combined market forecast ($m), 2019—24 …………… 3-18
Exhibit 3-12: Semi-rigid/dynamic stabilization pedicle screw systems, global market forecast ($m), 2019—24…………………………………………………………….. 3-20
Exhibit 3-13: Interspinous process decompression devices, global market forecast ($m), 2019—24 ……………………………………………………………………………………………………… 3-22
Exhibit 3-14: Interspinous process decompression devices market ($m), share by supplier, 2019 …………………………………………………………………………………………………………….. 3-25
Exhibit 3-15: Boston Scientific net sales ($m), by product category and geography, 2017—19 ……………………………………………………………………………………………………… 3-26
Exhibit 3-16: Dynamic stabilization/semi-rigid pedicle screw systems market ($m), share by supplier, 2019…………………………………………………………………………………… 3-28
Exhibit 3-17: Globus Medical net sales ($’000), by product category and region, 2017–19……….. 3-29
Exhibit 3-18: Zimmer Biomet net sales ($m), by product category and region, 2017–19…………… 3-30
Exhibit 3-19: Facet joint anatomy ………………………………………………………………………………………. 3-31
Exhibit 3-20: ACADIA Facet Replacement System …………………………………………………………………. 3-32
Exhibit 3-21: The TOPS System …………………………………………………………………………………………… 3-33
Exhibit 3-22: Selected facet replacement product(s) …………………………………………………………….. 3-34
Exhibit 3-23: Facet replacement under development……………………………………………………………. 3-35
4. Vertebroplasty and Kyphoplasty Devices …………………………………………………………………………… 4-1
4.1 Vertebroplasty………………………………………………………………………………………………………… 4-1
4.1.1 Clinical evidence and guidelines……………………………………………………………. 4-2
4.1.2 Polymethylmethacrylate alternatives…………………………………………………….. 4-4
4.1.3 Products…………………………………………………………………………………………….. 4-5
4.1.4 Market forecast ………………………………………………………………………………….. 4-8
4.1.5 Competitive analysis………………………………………………………………………….. 4-10
4.2 Kyphoplasty ………………………………………………………………………………………………………….. 4-14
4.2.1 Clinical evidence and guidelines………………………………………………………….. 4-15
4.2.2 Products…………………………………………………………………………………………… 4-15
4.2.3 Market forecast ………………………………………………………………………………… 4-17
4.2.4 Competitive analysis………………………………………………………………………….. 4-19
4.3 Vertebroplasty and Kyphoplasty, combined market analysis………………………………………. 4-22
4.4 Bibliography………………………………………………………………………………………………………….. 4-28
Exhibit 4-1: Stryker’s Cortoss bone augmentation material…………………………………………………….. 4-5
Exhibit 4-2: Medtronic’s Kyphon V Premium Vertebroplasty system ……………………………………….. 4-6
Exhibit 4-3: Selected vertebroplasty products………………………………………………………………………… 4-7
Exhibit 4-4: Vertebroplasty systems, global market forecast ($m), 2019—24…………………………….. 4-9
Exhibit 4-5: Vertebroplasty systems market, share by supplier ($m), 2019………………………………. 4-11
Exhibit 4-6: Stryker net sales ($m), by product category and geography, 2017–19…………………… 4-12
Exhibit 4-7: Medtronic net sales ($m), by product category and geography, 2017–19 ……………… 4-13
Exhibit 4-8: Globus Medical’s Affirm kyphoplasty system………………………………………………………. 4-14
Exhibit 4-9: Selected kyphoplasty systems and their features………………………………………………… 4-16
Exhibit 4-10: Balloon kyphoplasty systems, market forecast ($m), 2019—24…………………………… 4-18
Exhibit 4-11: Kyphoplasty systems market ($m), share by supplier, 2019………………………………… 4-20
Exhibit 4-12: Medtronic net sales ($m), by product category and geography, 2017–19 ……………. 4-21
Exhibit 4-13: Stryker net sales ($m), by product category and geography, 2017–19…………………. 4-22
Exhibit 4-14: Percutaneous vertebral augmentation systems, combined market forecast ($m), 2019—24 ………………………………………………………. 4-23
Exhibit 4-15: Cost of vertebroplasty and kyphoplasty kits ……………………………………………………… 4-25
Exhibit 4-16: Vertebroplasty and kyphoplasty US Medicare reimbursement, outpatient, physician office, and ambulatory surgery center, 2019……………………… 4-26
Exhibit 4-17: Vertebroplasty and kyphoplasty US Medicare reimbursement, outpatient, physician office, and ambulatory surgery center, 2020……………………… 4-26
Exhibit 4-18: Vertebral compression fracture, hospital inpatient, 2019 …………………………………… 4-27
Exhibit 4-19: Vertebral compression fracture, hospital inpatient, 2020 …………………………………… 4-27
APPENDIX: COMPANY LISTING……………………………………………………………………………………………………..A-1
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