In Vivo uses Scrip’s ranking of Top 100 pharma companies (based on sales figures for 2017) to report on the companies in the top 20 of the list. Get an inside look at the rankings, which saw Shire PLC move up to join the top 20 for the first time on the eve of their takeover by Takeda. See what other companies moved up (and which dropped in rank), and what criteria was used to rate them. You’ll see the effect that R&D spend had on overall rankings, and get a glimpse into how this year’s rankings might presage future