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This comprehensive medical market and technology report provides an overview and in-depth market analysis of the global market for transcatheter embolization and occlusion devices.
Highlights
Key topics covered
Sales of cerebral aneurysm/AVM embolization devices totaled just over $1bn in 2018, with sales expected to climb at a CAGR of 4.1% through 2023. Advances in imaging screening techniques have led to increased intervention rates for these disorders, particularly in developed countries. Embolic coils accounted for nearly three quarters of sales in this market; however, flow diverters are expected to experience the most growth over the forecast period. In the peripheral vascular embolization devices market, sales also totaled just over $1bn in 2018, and are expected to increase at a CAGR of 5.1% over the forecast period, with growth largely attributed to increased use of radiolabelled and drug-eluting beads, and the increasing penetration rate of detachable embolization coils.
This analysis includes a discussion of products, current/forecast markets, and competitors in the global markets for cerebral aneurysm/AVM embolization systems (eg embolic coils, liquid embolics, neuroendovascular stents, and flow diversion systems) and peripheral embolization systems (eg peripheral coils, vascular plugs, liquid embolics, and particles/microspheres). This report provides forecasts for the US, five major European markets (France, Germany, Italy, Spain, and the UK), Japan, and the rest of world markets for 2018–23.
Executive Summary ………………………………………………………………………. ES-1
i. Embolization and occlusion systems……………………………………………………………………….ES-1
a. Cerebral aneurysm and AVM embolization devices……………………………………..ES-1
b. Peripheral vascular disease embolization and occlusion devices……………………ES-4
ii. Market leaders……………………………………………………………………………………………………ES-6
iii. Methodology……………………………………………………………………………………………………..ES-6
Exhibit ES-1: Embolization systems for the treatment of cerebral aneurysms and AVMs, combined market forecast ($m), by country/region, 2018–23 ……………………………………..ES-3
Exhibit ES-2: Embolization systems for the treatment of peripheral aneurysms, AVMs, tumors, and fibroids, combined market forecast ($m), by region, 2018–23……………………………….ES-5
1. Clinical Overview …………………………………………………………………………1-1
1.1 Interventional neuroradiology…………………………………………………………………………….. 1-1
1.1.1 Hemorrhagic stroke …………………………………………………………………………….. 1-1
1.1.2 Cerebral aneurysm………………………………………………………………………………. 1-3
1.1.3 Arteriovenous malformations……………………………………………………………….. 1-3
1.1.4 Arteriovenous fistulae …………………………………………………………………………. 1-4
1.1.5 Repair of cranial aneurysms, AVMs, and fistulae …………………………………….. 1-5
1.2 Peripheral vascular conditions…………………………………………………………………………….. 1-9
1.2.1 Peripheral aneurysms………………………………………………………………………….. 1-9
1.2.2 Peripheral AVMs……………………………………………………………………………….. 1-10
1.2.3 Repair of peripheral aneurysms, AVMs, and fistulae ……………………………… 1-11
1.3 Other conditions treated by embolization ………………………………………………………….. 1-11
1.3.1 Tumors…………………………………………………………………………………………….. 1-11
1.3.2 Uterine fibroids…………………………………………………………………………………. 1-12
1.4 Bibliography ……………………………………………………………………………………………………. 1-14
Exhibit 1-1: Clinical features and characteristics of hemorrhagic stroke ……………………………………. 1-2
Exhibit 1-2: Incident cases of hemorrhagic stroke, by subtype, US, 5EU, and Japan, 2018 and 2023 ……………………………………………………………………………………………………….. 1-3
Exhibit 1-3: Illustration of an embolic coil procedure for a cerebral aneurysm…………………………… 1-6
Exhibit 1-4: Illustration of an endovascular embolization procedure for an AVM……………………….. 1-7
2. Embolization and Occlusion Products………………………………………………2-1
2.1 Neurovascular embolization products………………………………………………………………….. 2-1
2.1.1 Microcoil embolization products…………………………………………………………… 2-2
2.1.2 Liquid embolics…………………………………………………………………………………… 2-3
2.1.3 Stent products for wide-neck aneurysms……………………………………………….. 2-5
2.1.4 Flow diversion devices…………………………………………………………………………. 2-7
2.1.5 Balloon-assisted embolization ………………………………………………………………. 2-9
2.1.6 Flow disruption and other novel/emerging aneurysm embolization devices………………………………………………………………… 2-10
2.1.7 Current clinical trials………………………………………………………………………….. 2-12
2.2 Peripheral embolization products ……………………………………………………………………… 2-15
2.2.1 Coils ………………………………………………………………………………………………. 2-15
2.2.2 Liquid embolics…………………………………………………………………………………. 2-17
2.2.3 Particles……………………………………………………………………………………………. 2-19
2.2.4 Vascular plugs…………………………………………………………………………………… 2-21
2.2.5 Gelatin……………………………………………………………………………………………… 2-23
2.2.6 Balloon-assisted embolization …………………………………………………………….. 2-23
2.3 Bibliography ……………………………………………………………………………………………………. 2-24
Exhibit 2-1: Advantages and disadvantages of cerebral aneurysm clipping versus coiling procedures…………………………………………………………………………………………………… 2-1
Exhibit 2-2: Selected neuroendovascular aneurysm microcoils, 2020 ……………………………………….. 2-3
Exhibit 2-3: Selected neuroendovascular liquid embolics, 2020 ……………………………………………….. 2-4
Exhibit 2-4: Selected neuroendovascular stents for the treatment of wide-neck aneurysms, 2020…………………………………………………………………………………………………….. 2-6
Exhibit 2-5: Selected flow diversion devices, 2020………………………………………………………………….. 2-9
Exhibit 2-6: Selected flow disruption and other novel embolic systems, 2020………………………….. 2-12
Exhibit 2-7: Selected clinical trials of neuroendovascular embolic systems for aneurysms and AVMs, 2020……………………………………………………………………………………………………. 2-13
Exhibit 2-8: Selected peripheral embolization coils, 2020………………………………………………………. 2-16
Exhibit 2-9: Selected liquid embolics used in/under development for peripheral applications, 2020…………………………………………………………………………………………………. 2-19
Exhibit 2-10: Selected embolic beads and particles, 2020 ……………………………………………………… 2-20
Exhibit 2-11: Selected vascular plugs, 2020………………………………………………………………………….. 2-23
3. Market for Transcatheter Embolization and Occlusion Devices……………3-1
3.1 Combined market forecast …………………………………………………………………………………. 3-1
3.2 Cerebral aneurysm and AVM embolization systems………………………………………………. 3-3
3.2.1 Market forecast ………………………………………………………………………………….. 3-3
3.2.2 Procedure volumes forecast…………………………………………………………………. 3-7
3.2.3 Competitive analysis……………………………………………………………………………. 3-8
3.2.4 Embolic coiling: procedure/market/competitive analyses………………………. 3-10
3.2.5 Liquid embolics: procedure/market/competitive analyses……………………… 3-14
3.2.6 Neuroendovascular stents for stent-assisted coiling: procedure/market/ competitive analyses………………………………………………………………… 3-18
3.2.7 Flow diversion, flow disruption, and other embolic systems: procedure/ market/competitive analyses…………………………………………………….. 3-22
3.3 Peripheral embolization systems……………………………………………………………………….. 3-27
3.3.1 Peripheral coiling systems: procedure/market/competitive analyses………. 3-27
3.3.2 Vascular plugs: procedure/market/competitive analyses……………………….. 3-32
3.3.3 Liquid embolics: procedure/market/competitive analyses……………………… 3-37
3.3.4 Particles and microspheres: procedure/market/competitive analyses …….. 3-41
3.4 Bibliography ……………………………………………………………………………………………………. 3-47
Exhibit 3-1: Transcatheter embolization and occlusion devices, combined market forecast, by country/region, 2018–23 …………………………………………………………………………………….. 3-2
Exhibit 3-2: Embolization systems for the treatment of cerebral aneurysms and AVMs, combined market forecast ($m), by country/region, 2018–23 ……………………………………… 3-4
Exhibit 3-3: Embolization systems for the treatment of cerebral aneurysms and AVMs, combined market forecast ($m), by product segment, 2018–23…………………………………… 3-6
Exhibit 3-4: Neuroendovascular embolization, procedure volumes forecast, by type of embolic system, 2018–23 ………………………………………………………………………………………… 3-7
Exhibit 3-5: Neuroendovascular embolization, procedure volumes forecast, by country/region, 2018–23 …………………………………………………………………………………….. 3-8
Exhibit 3-6: Cerebral aneurysm and AVM embolization systems market, share by supplier, 2018……………………………………………………………………………………………. 3-9
Exhibit 3-7: Embolic coiling, procedure volumes forecast, by country/region, 2018–23…………….. 3-11
Exhibit 3-8: Neuroendovascular coiling systems, market forecast, by country/region, 2018–23…. 3-12
Exhibit 3-9: Neuroendovascular coiling systems market, share by supplier, 2018 …………………….. 3-14
Exhibit 3-10: Neuroendovascular liquid embolics, procedure volumes forecast, by country/region, 2018–23 …………………………………………………………………………………… 3-15
Exhibit 3-11: Neuroendovascular liquid embolics, market forecast, by country/region, 2018–23 …………………………………………………………………………………… 3-16
Exhibit 3-12: Neuroendovascular liquid embolics market, share by supplier, 2018 …………………… 3-18
Exhibit 3-13: Stent-assisted coiling, procedure volumes forecast, by country/region, 2018–23….. 3-19
Exhibit 3-14: Coil-containment stents for intracranial applications, market forecast ($m), by country/region, 2018–23 …………………………………………………………………………………… 3-20
Exhibit 3-15: Market for coil-containment stents for intracranial applications, share by supplier, 2018………………………………………………………………………………………….. 3-22
Exhibit 3-16: Flow diversion and other embolization procedures, procedure volumes forecast, by country/region, 2018–23 …………………………………………………………………………………… 3-23
Exhibit 3-17: Flow diversion and other newly developed embolization systems, market forecast ($m), by country/region, 2018–23 …………………………………………………… 3-24
Exhibit 3-18: Market for flow diversion and other newly developed embolization products, share by supplier, 2018………………………………………………………………………………………….. 3-27
Exhibit 3-19: Peripheral coiling, procedure volumes forecast, by country/region, 2018–23……….. 3-29
Exhibit 3-20: Peripheral coils, market forecast ($m), by country/region, 2018–23 ……………………. 3-30
Exhibit 3-21: Market for peripheral coil products, share by supplier, 2018………………………………. 3-32
Exhibit 3-22: Vascular plugs, procedure volumes forecast, by country/region, 2018–23……………. 3-33
Exhibit 3-23: Vascular plugs, market forecast ($m), by country/region, 2018–23……………………… 3-35
Exhibit 3-24: Market for vascular plug products, share by supplier, 2018………………………………… 3-36
Exhibit 3-25: Liquid embolics for peripheral use, procedure volumes forecast, by country/region, 2018–23 …………………………………………………………………………………… 3-37
Exhibit 3-26: Liquid embolics for peripheral use, market forecast ($m), by country/region, 2018–23 …………………………………………………………………………………… 3-39
Exhibit 3-27: Market for liquid embolics for peripheral use, share by supplier, 2018 ………………… 3-41
Exhibit 3-28: Embolic particle and microsphere procedures, procedure volumes forecast, by country/region, 2018–23 …………………………………………………………………………………… 3-43
Exhibit 3-29: Embolic particles and microspheres, market forecast ($m), by country/region, 2018–23 …………………………………………………………………………………… 3-44
Exhibit 3-30: Market for embolic particles and microspheres, share by supplier, 2018……………… 3-46
Appendix: Company Listing……………………………………………………………… A-1
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