U.S. Markets for Interventional Peripheral Vascular Disease Management Products and Technologies
U.S. Markets for Interventional Peripheral Vascular Disease Management Products and Technologies
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This dynamic, new report from Medtech Insight includes analyses of products, current and forecast markets, competitors, and opportunities in the U.S. interventional peripheral vascular disease management arena.
Publisher: Medtech Insight
- Description
- Contents
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Peripheral vascular disease (PVD) refers to those conditions that affect the vessels carrying blood to and from the extremities as well as the tissues and organs of the abdominal and pelvic cavities. The most commonly diagnosed form of PVD is plaque-related peripheral artery disease; among the other types of PVD are chronic venous insufficiency, deep vein thrombosis, and pulmonary embolism.
In 2012, approximately 3.8 million interventional procedures for the diagnosis and treatment of PVD were performed in the United States (U.S.), generating an estimated $1.67 billion in corresponding product sales. The number of diagnostic and therapeutic interventions for PVD management is expected to increase at a compound annual rate of 2.0% during the forecast period covered by this report, reaching nearly 4.2 million in the year 2013. Sales of products to perform these interventional procedures are projected to increase at a compound annual rate of 6.0% during the forecast period covered by this report, reaching an estimated $2.2 billion in the year 2013.
This dynamic, new report from Medtech Insight includes analyses of products, current and forecast markets, competitors, and opportunities in the U.S. interventional peripheral vascular disease management arena.
Covered topics in this report include angiography devices; catheter-directed thrombolysis products; drug-eluting balloon systems; cryotherapy products; endovascular embolization products; intravascular ultrasound systems; mechanical atherectomy systems; thrombectomy products; noninvasive peripheral vascular disease treatments; peripheral transluminal angioplasty devices; surgical/endoscopic peripheral vascular disease treatments; vascular puncture closure devices; and vena cava filters, among others.
Table of Contents
1. PERIPHERAL VASCULAR DISEASE OVERVIEW ……………………………… 1-1
1.1 Anatomy and Physiology of the Circulatory System …………………….. 1-1
1.2 Types of Peripheral Vascular Disease……………………………………….. 1-5
1.2.1 Peripheral Artery Disease………………………………………….. 1-5
1.2.1.1 Etiology ……………………………………………………. 1-5
1.2.1.2 Epidemiology…………………………………………….. 1-8
1.2.2 Aneurysm ……………………………………………………………….. 1-9
1.2.2.1 Etiology ……………………………………………………. 1-9
1.2.2.2 Epidemiology…………………………………………… 1-12
1.2.3 Deep Vein Thrombosis and Pulmonary Embolism ………. 1-14
1.2.3.1 Etiology ………………………………………………….. 1-16
1.2.3.2 Epidemiology…………………………………………… 1-16
1.2.4 Chronic Venous Insufficiency …………………………………… 1-17
1.2.4.1 Etiology ………………………………………………….. 1-17
1.2.4.2 Epidemiology…………………………………………… 1-22
Exhibit 1-1: 2013, Peripheral Artery Disease, Facts and Figures ………………….. 1-10
Exhibit 1-2: 2013, Aortic Aneurysm, Facts and Figures……………………………….. 1-15
Exhibit 1-3: 2013, Deep Vein Thrombosis, Facts and Figures ……………………… 1-18
Exhibit 1-4: Classification of Chronic Venous Insufficiency ………………………….. 1-21
Exhibit 1-5: 2013, Chronic Venous Insufficiency, Facts and Figures……………… 1-24
2. INTERVENTIONAL PERIPHERAL VASCULAR DISEASE
DIAGNOSTIC PRODUCTS MARKET ………………………………………………… 2-1
2.1 Noninvasive Peripheral Vascular Disease Diagnostics ………………… 2-3
2.1.1 Ankle/Brachial Index…………………………………………………. 2-3
2.1.2 Exercise Tolerance Testing……………………………………….. 2-6
2.1.3 Imaging Methods……………………………………………………… 2-6
2.1.3.1 Computed Tomography………………………………. 2-6
2.1.3.2 Magnetic Resonance Imaging……………………. 2-10
2.1.3.3 Diagnostic Ultrasound Imaging…………………… 2-14
2.1.4 Photoplethysmography and Air Plethysmography……….. 2-21
U.S. Markets for Interventional Technologies
2.2 Interventional Peripheral Vascular Disease Diagnostics,
Market Analysis ……………………………………………………………………. 2-22
2.2.1 Angiography ………………………………………………………….. 2-23
2.2.1.1 Types …………………………………………………….. 2-24
2.2.1.1.1 Peripheral Arterial
Angiography…………………………. 2-24
2.2.1.1.2 Peripheral Venous
Angiography…………………………. 2-27
2.2.1.1.3 Ascending and Descending
Venography …………………………. 2-28
2.2.1.1.4 Venographic Applications for Deep
Vein Thrombosis in Lower and
Upper Extremities …………………. 2-28
2.2.1.2 Procedures/Technologies………………………….. 2-30
2.2.1.3 Products …………………………………………………. 2-31
2.2.1.4 Market Forecast ………………………………………. 2-33
2.2.1.5 Competitors…………………………………………….. 2-33
2.2.2 Intravascular Ultrasound………………………………………….. 2-50
2.2.2.1 Procedures/Technologies………………………….. 2-51
2.2.2.2 Products …………………………………………………. 2-55
2.2.2.3 Market Forecast ………………………………………. 2-56
2.2.2.4 Competitors…………………………………………….. 2-62
Exhibit 2-1: Interventional Peripheral Vascular Disease Diagnosis,
Combined Procedure Volumes Forecast, 2012-2017…………………… 2-2
Exhibit 2-2: Interventional Peripheral Vascular Disease Diagnostic Products,
Combined Market Forecast, 2012-2017 …………………………………….. 2-4
Exhibit 2-3: Peripheral Angiography, Procedure Volumes Forecast,
2012-2017 …………………………………………………………………………… 2-32
Exhibit 2-4: 2013, Selected Angiography Catheters……………………………………. 2-34
Exhibit 2-5: 2013, Selected Diagnostic Guidewires…………………………………….. 2-39
Exhibit 2-6: 2013, Selected Introducers/Sheaths………………………………………… 2-43
Exhibit 2-7: Angiography Devices for Peripheral Vascular
Disease Diagnostics, Market Forecast, 2012-2017 ……………………. 2-46
Exhibit 2-8: 2012, Market for Angiography Devices for Peripheral Vascular
Disease Diagnostics, Share by Supplier…………………………………… 2-49
Exhibit 2-9: Intravascular Ultrasound, Procedure Volumes Forecast,
2012-2017 …………………………………………………………………………… 2-54
Exhibit 2-10: 2013, Selected Intravascular Ultrasound Catheters and Systems… 2-57
Exhibit 2-11: Intravascular Ultrasound Products, Market Forecast,
2012-2017 …………………………………………………………………………… 2-64
Exhibit 2-12: 2012, Intravascular Ultrasound Products Market,
Share by Supplier…………………………………………………………………. 2-66
3. INTERVENTIONAL PERIPHERAL VASCULAR DISEASE
TREATMENT PRODUCTS MARKET…………………………………………………. 3-1
3.1 Noninvasive Peripheral Vascular Disease Treatments…………………. 3-2
3.2 Surgical/Endoscopic Peripheral Vascular Disease Treatments……… 3-9
3.2.1 Peripheral Artery Surgery………………………………………….. 3-9
3.2.1.1 Aortofemoral Bypass Graft Surgery…………………………… 3-10
3.2.1.2 Distal Tibial-Peroneal Vascular Reconstruction…………… 3-11
3.2.1.3 Femoropopliteal Bypass Graft Surgery ……………………… 3-11
3.2.2 Thromboendarterectomy …………………………………………. 3-12
3.2.3 Chronic Venous Insufficiency and
Venous Ulceration Treatments…………………………………. 3-12
3.2.3.1 Deep Vein Reconstruction…………………………. 3-13
3.2.3.2 Open Subfascial Perforator Surgery……………. 3-13
3.2.3.3 Sclerotherapy ………………………………………….. 3-14
3.2.3.4 Skin Grafting……………………………………………. 3-14
3.2.3.5 Subfascial Endoscopic Perforator Surgery…… 3-15
3.2.3.6 Superficial Vein Stripping ………………………….. 3-15
3.3 Interventional Peripheral Vascular Disease Treatments,
Market Analysis ……………………………………………………………………. 3-16
3.3.1 Percutaneous Transluminal Angioplasty ……………………. 3-16
3.3.1.1 Procedures/Technologies………………………….. 3-16
3.3.1.2 Products …………………………………………………. 3-21
3.3.1.2.1 Balloon Catheters …………………. 3-21
3.3.1.2.2 Guiding Catheters…………………. 3-23
3.3.1.2.3 Guidewires…………………………… 3-35
3.3.1.2.4 Introducers/Sheaths………………. 3-36
3.3.1.2.5 Accessories …………………………. 3-37
3.3.1.2 Market Forecast ………………………………………. 3-38
3.3.1.3 Competitors…………………………………………….. 3-39
U.S. Markets for Interventional Technologies
3.3.2 Catheter-Directed Thrombolysis……………………………….. 3-44
3.3.2.1 Procedures/Technologies………………………….. 3-44
3.3.2.2 Products …………………………………………………. 3-45
3.3.2.3 Market Forecast ………………………………………. 3-50
3.3.2.4 Competitors…………………………………………….. 3-50
3.3.3 Mechanical Atherectomy …………………………………………. 3-50
3.3.3.1 Procedures/Technologies………………………….. 3-53
3.3.3.2 Products …………………………………………………. 3-53
3.3.3.3 Market Forecast ………………………………………. 3-60
3.3.3.4 Competitors…………………………………………….. 3-60
3.3.4 Endovascular Embolization ……………………………………… 3-64
3.3.4.1 Procedures/Technologies………………………….. 3-64
3.3.4.2 Products …………………………………………………. 3-66
3.3.4.3 Market Forecast ………………………………………. 3-69
3.3.4.4 Competitors…………………………………………….. 3-74
3.3.5 Thrombectomy ………………………………………………………. 3-77
3.3.5.1 Procedures/Technologies………………………….. 3-79
3.3.5.2 Products …………………………………………………. 3-80
3.3.5.3 Market Forecast ………………………………………. 3-82
3.3.5.4 Competitors…………………………………………….. 3-82
3.3.6 Vena Cava Filter Placement…………………………………….. 3-86
3.3.6.1 Procedures/Technologies………………………….. 3-86
3.3.6.2 Products …………………………………………………. 3-89
3.3.6.3 Market Forecast ………………………………………. 3-92
3.3.6.4 Competitors…………………………………………….. 3-92
3.3.7 Vascular Puncture Hemostasis
Tools and Techniques …………………………………………….. 3-97
3.3.7.1 Procedures/Technologies………………………….. 3-97
3.3.7.2 Products ……………………………………………….. 3-100
3.3.7.3 Market Forecast …………………………………….. 3-103
3.3.7.4 Competitors…………………………………………… 3-108
3.3.8 Cryotherapy………………………………………………………… 3-108
3.3.8.1 Procedures/Technologies………………………… 3-111
3.3.8.2 Products ……………………………………………….. 3-113
3.3.8.3 Market Forecast …………………………………….. 3-115
Exhibit 3-1: Interventional Peripheral Vascular Disease Treatment,
Combined Procedure Volumes Forecast, 2012-2017…………………… 3-3
Exhibit 3-2: Interventional Peripheral Vascular Disease Treatment Products,
Combined Market Forecast, 2012-2017 …………………………………….. 3-5
Exhibit 3-3: Percutaneous Transluminal Angioplasty,
Procedure Volumes Forecast, 2012-2017………………………………… 3-19
Exhibit 3-4: 2013, Selected Percutaneous Transluminal Angioplasty
Balloon Catheters…………………………………………………………………. 3-24
Exhibit 3-5: Percutaneous Transluminal Angioplasty Devices,
Market Forecast, 2012-2017 ………………………………………………….. 3-40
Exhibit 3-6: 2012, Percutaneous Transluminal Angioplasty Devices Market,
Share by Supplier…………………………………………………………………. 3-43
Exhibit 3-7: Catheter-Directed Thrombolysis, Procedure Volumes Forecast,
2012-2017 …………………………………………………………………………… 3-46
Exhibit 3-8: 2013, Selected Catheter-Directed Thrombolysis Systems ………….. 3-48
Exhibit 3-9: Catheter-Directed Thrombolysis Systems, Market Forecast,
2012-2017 …………………………………………………………………………… 3-51
Exhibit 3-10: 2012, Catheter-Directed Thrombolysis Systems Market,
Share by Supplier…………………………………………………………………. 3-52
Exhibit 3-11: Mechanical Atherectomy, Procedure Volumes Forecast,
2012-2017 …………………………………………………………………………… 3-54
Exhibit 3-12: 2013, Selected Mechanical Atherectomy Systems…………………….. 3-57
Exhibit 3-13: Mechanical Atherectomy Systems, Market Forecast, 2012-2017…. 3-61
Exhibit 3-14: 2012, Mechanical Atherectomy Systems, Share by Supplier ………. 3-63
Exhibit 3-15: Endovascular Embolization, Procedure Volumes Forecast,
2012-2017 …………………………………………………………………………… 3-67
Exhibit 3-16: 2013, Selected Endovascular Embolization Products ………………… 3-70
Exhibit 3-17: Endovascular Embolization Products, Market Forecast,
2012-2017 …………………………………………………………………………… 3-75
Exhibit 3-18: 2012, Endovascular Embolization Products Market,
Share by Supplier…………………………………………………………………. 3-78
Exhibit 3-19: Thrombectomy, Procedure Volumes Forecast, 2012-2017 …………. 3-81
Exhibit 3-20: 2013, Selected Thrombectomy Systems………………………………….. 3-83
Exhibit 3-21: Thrombectomy, Market Forecast, 2012-2017……………………………. 3-85
Exhibit 3-22: 2012, Thrombectomy Systems Market, Share by Supplier………….. 3-87
Exhibit 3-23: Vena Cava Filter Placement, Procedure Volumes Forecast,
2012-2017 …………………………………………………………………………… 3-90
Exhibit 3-24: 2013, Selected Vena Cava Filter Systems ……………………………….. 3-93
Exhibit 3-25: Vena Cava Filter Systems, Market Forecast, 2012-2017 ……………. 3-96
Exhibit 3-26: 2012, Vena Cava Filter Systems Market, Share by Supplier……….. 3-98
Exhibit 3-27: Vascular Puncture Closure Systems, Procedure Volumes
Forecast, 2012-2017 …………………………………………………………… 3-101
Exhibit 3-28: 2013, Selected Vascular Puncture Closure Systems ……………….. 3-104
Exhibit 3-29: Vascular Puncture Closure Systems, Market Forecast,
2012-2017 …………………………………………………………………………. 3-109
Exhibit 3-30: 2012, Vascular Puncture Closure Systems Market,
Share by Supplier……………………………………………………………….. 3-110
Exhibit 3-31: Endovascular Cryotherapy, Procedure Volumes Forecast,
2012-2017 …………………………………………………………………………. 3-114
Exhibit 3-32: Endovascular Cryotherapy Systems, Market Forecast,
2012-2017 …………………………………………………………………………. 3-116
4. COMPANY PROFILES…………………………………………………………………….. 4-1
4.1 Abbott Laboratories ………………………………………………………………… 4-1
4.2 AccessClosure, Inc…………………………………………………………………. 4-2
4.3 AngioDynamics, Inc………………………………………………………………… 4-2
4.4 Arrow International/Teleflex, Inc. ………………………………………………. 4-4
4.5 C.R. Bard, Inc………………………………………………………………………… 4-5
4.6 Boston Scientific Corporation …………………………………………………… 4-6
4.7 B. Braun Melsungen AG………………………………………………………….. 4-9
4.8 Cardiovascular Systems, Inc. …………………………………………………. 4-10
4.9 Cardiva Medical, Inc……………………………………………………………… 4-11
4.10 Cook Medical/Cook Group …………………………………………………….. 4-12
4.11 Cordis Corporation/Johnson & Johnson…………………………………… 4-13
4.12 Covidien ……………………………………………………………………………… 4-15
4.13 MEDRAD, Inc./Bayer HealthCare/Bayer Group ………………………… 4-17
4.14 Merit Medical Systems, Inc…………………………………………………….. 4-18
4.15 Spectranetics Corporation……………………………………………………… 4-19
4.16 St. Jude Medical, Inc. ……………………………………………………………. 4-20
4.17 Terumo Interventional Systems/Terumo Corporation…………………. 4-20
4.18 Volcano Corporation……………………………………………………………… 4-21 APPENDIX: COMPANY LISTING……………………………………………………………… A-1
Figure: Interventional Peripheral Vascular Disease Management, Combined Procedure Volumes Forecast, 2012-2017
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