U.S. Markets for Stroke Management
U.S. Markets for Stroke Management
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The United States (U.S.) market for stroke management products, which encompasses diagnostic and therapeutic systems, is a market composed of old and new technologies that are often used together in order to prevent and treat stroke. Improvements in stroke diagnostic systems will facilitate the delivery of timely stroke therapies within the optimum treatment window for patients suffering from stroke.
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The United States (U.S.) market for stroke management products, which encompasses diagnostic and therapeutic systems, is a market composed of old and new technologies that are often used together in order to prevent and treat stroke. Improvements in stroke diagnostic systems will facilitate the delivery of timely stroke therapies within the optimum treatment window for patients suffering from stroke. Topics covered in this report include:
- diagnostic, interventional, and pharmaceutical stroke-related products;
- procedure and market forecasts for the years 2014 to 2019;
- key factors influencing the growth of individual product markets;
- estimated market shares and sales among major U.S. suppliers;
- major supplier product portfolio analysis in individual product markets; and,
- emerging technology that could potentially change the way stroke is diagnosed and treated, which could potentially change how product markets develop.
Over the forecast period covered in this report (2014 through 2019), the estimated value of the U.S. market for stroke management systems (not including pharmaceutical agents) is expected to grow by approximately $284.2 million at compound annual growth rate (CAGR) of 5.1%; for the overall stroke management market; diagnostic imaging products are forecasted to grow at a CAGR of 3.6%, while surgical and endovascular products will grow at a CAGR of 5.4%.
U.S. Markets for Stroke Management Table of Contents
EXECUTIVE SUMMARY…………………………………………………………………………. ES-1
i. Methodology……………………………………………………………………….. ES-2
Exhibit ES-1: 2014, U.S. Stroke Management Market, Shares by Product Markets ………………………………………………………………….. ES-3
1. CLINICAL OVERVIEW…………………………………………………………………….. 1-1
1.1 Ischemic Stroke……………………………………………………………………… 1-1
1.1.1 Symptoms and Risk Factors………………………………………. 1-3
1.1.2 Transient Ischemic Attack …………………………………………. 1-5
1.2 Hemorrhagic Stroke………………………………………………………………… 1-5
1.2.1 Symptoms and Risk Factors………………………………………. 1-8
1.2.2 Cerebral Aneurysm ………………………………………………… 1-12
1.2.3 Arteriovenous Malformations……………………………………. 1-12
Exhibit 1-1: 2015, Clinical Features and Characteristics of Ischemic Stroke…….. 1-6
Exhibit 1-2: 2015, Clinical Features and Characteristics of Hemorrhagic Stroke………………………………………………………………. 1-11
Exhibit 1-3: 2015, Cerebral Aneurysm, Facts and Figures …………………………… 1-14
2. CLINICAL MANAGEMENT OF STROKE……………………………………………. 2-1
2.1 Stroke Diagnostics and Diagnostic Imaging ……………………………….. 2-1
2.1.1 Computed Tomography…………………………………………….. 2-3
2.1.1.1 Stroke-Related Applications of Computed Tomography ……………………………………………… 2-4
2.1.2 Magnetic Resonance Imaging ……………………………………. 2-5
2.1.2.1 Stroke-Related Applications of Magnetic Resonance Imaging …………………………………… 2-8
2.1.3 Diagnostic Ultrasound …………………………………………….. 2-10
2.1.3.1 Stroke-Related Applications of Diagnostic Ultrasound………………………………………………. 2-11
2.1.4 Cerebral Angiography …………………………………………….. 2-12
2.1.4.1 Stroke-Related Applications of Cerebral Angiography ……………………………………………. 2-13
2.1.5 Nuclear Medicine Imaging……………………………………….. 2-14
2.1.5.1 Gamma Camera Imaging ………………………….. 2-14
2.1.5.2 Positron Emission Tomography………………….. 2-15
2.1.5.3 Stroke-Related Applications of Nuclear Medicine Imaging …………………………………….. 2-16
2.2 Therapeutic Management of Stroke ………………………………………… 2-17
2.2.1 Pharmacologic Preventative and Therapeutic Modalities ……………………………………………. 2-18
2.2.1.1 Anticoagulation Drug Therapy……………………. 2-18
2.2.1.2 Antihypertensive Drug Therapy………………….. 2-19
2.2.1.3 Antiplatelet Drug Therapy………………………….. 2-21
2.2.1.4 Thrombolytic Drug Therapy……………………….. 2-23
2.2.2 Surgical and Endovascular Interventions …………………… 2-24
2.2.2.1 Carotid Artery Stenosis …………………………….. 2-24
2.2.2.1.1 Carotid Endarterectomy …………. 2-24
2.2.2.1.2 Carotid Artery Stenting…………… 2-25
2.2.2.2 Intracranial Aneurysms and Arteriovenous Malformations………………………………………….. 2-27
2.2.2.2.1 Surgical Repair …………………….. 2-29
2.2.2.2.1.1 Surgical Repair of Aneurysms ……. 2-29
2.2.2.2.1.2 Surgical Repair of Arteriovenous Malformations……. 2-31
2.2.2.2.2 Endovascular Embolization…….. 2-33
2.2.2.2.3 Gamma Knife System……………. 2-33
2.2.2.2.4 Intracranial Stenting Systems …. 2-36
2.2.2.2.4.1 Intracranial Stent Systems in Development …….. 2-37
2.2.2.2.5 Cerebral Thrombectomy Systems ………… 2-38
2.2.2.2.6 Flow Diverter Technology ………. 2-39
2.3 Emerging Therapies in Stroke Prevention and Management ………. 2-40
2.3.1 Cellular Therapy …………………………………………………….. 2-40
2.3.2 Intrasaccular Occlusion Devices ………………………………. 2-41
2.3.3 Sonothrombolysis…………………………………………………… 2-42
2.3.4 Cerebral Collateral Flow Enhancement Systems ………… 2-42
2.3.5 Neuroprotection Systems ………………………………………… 2-43
2.3.6 Other Thrombolytic Agents………………………………………. 2-44
Exhibit 2-1: Carotid Endarterectomy…………………………………………………………. 2-26
Exhibit 2-2: Carotid Artery Stenting ………………………………………………………….. 2-28
Exhibit 2-3: Embolic Coiling…………………………………………………………………….. 2-32
Exhibit 2-4: Endovascular Embolization ……………………………………………………. 2-34
3. STROKE MANAGEMENT PRODUCTS ……………………………………………… 3-1
3.1 Diagnostic Imaging Systems ……………………………………………………. 3-1
3.1.1 Computed Tomography Products……………………………….. 3-6
3.1.1.1 Market Forecast ………………………………………. 3-11
3.1.1.2 Competitive Analysis ………………………………… 3-12
3.1.2 Magnetic Resonance Imaging Products…………………….. 3-17
3.1.2.1 Market Forecast ………………………………………. 3-19
3.1.2.2 Competitive Analysis ………………………………… 3-21
3.1.3 Diagnostic Ultrasound Products ……………………………….. 3-25
3.1.3.1 Market Forecast ………………………………………. 3-27
3.1.3.2 Competitive Analysis ………………………………… 3-28
3.1.4 Nuclear Medicine Imaging Products………………………….. 3-36
3.1.4.1 Market Forecast ………………………………………. 3-36
3.1.4.2 Competitive Analysis ………………………………… 3-37
3.1.5 Cerebral Angiography Products ……………………………….. 3-45
3.1.5.1 Market Forecast ………………………………………. 3-45
3.1.5.2 Competitive Analysis ………………………………… 3-47
3.2 Drug Therapy Products …………………………………………………………. 3-51
3.2.1 Oral Anticoagulation Agents …………………………………….. 3-51
3.2.1.1 Market Forecast ………………………………………. 3-51
3.2.2 Oral Antihypertensive Agents …………………………………… 3-53
3.2.2.1 Market Forecast ………………………………………. 3-53
3.2.3 Oral Antiplatelet Agents…………………………………………… 3-54
3.2.3.1 Market Forecast ………………………………………. 3-54
3.2.4 Intravenous Thrombolytic Agents ……………………………… 3-55
3.2.4.1 Market Forecast ………………………………………. 3-55
3.3 Interventional Stroke Management Systems …………………………….. 3-56
3.3.1 Surgical and Endovascular Systems for Stroke Prophylaxis …………………………………………………. 3-56
3.3.1.1 Carotid Endarterectomy ……………………………. 3-61
3.3.1.1.1 Market Forecast ……………………. 3-61
3.3.1.2 Carotid Artery Stenting ……………………………… 3-62
3.3.1.2.1 Market Forecast ……………………. 3-62
3.3.1.2.2 Competitive Analysis……………… 3-68
3.3.1.3 Cerebral Aneurysm/Arteriovenous Malformation Surgical Clipping Systems………………………… 3-68
3.3.1.3.1 Market Forecast ……………………. 3-70
3.3.1.3.2 Competitive Analysis……………… 3-71
3.3.1.4 Cerebral Aneurysm/Arteriovenous Malformation Endovascular Embolization Systems ………….. 3-71
3.3.1.4.1 Market Forecast ……………………. 3-75
3.3.1.4.2 Competitive Analysis……………… 3-76
3.3.2 Cerebrovascular Endovascular Systems for Stroke Treatment……………………………………………………. 3-80
3.3.2.1 Cerebral Embolectomy/Mechanical Thrombectomy Products …………………………… 3-80
3.3.2.1.1 Market Forecast ……………………. 3-81
3.3.2.1.2 Competitive Analysis……………… 3-82
3.3.2.1.3 Emerging Cerebral Thrombectomy Systems ………… 3-85
3.3.2.2 Intracranial Stenting Systems…………………….. 3-87
3.3.2.2.1 Market Forecast ……………………. 3-87
3.3.2.3 Flow Diverter Technology………………………….. 3-90
3.3.2.3.1 Market Forecast ……………………. 3-90
3.3.2.3.2 Competitive Analysis……………… 3-91
Exhibit 3-1: Stroke Management Products, Combined Procedure Volumes Forecast, 2014-2019 …………………………………………………. 3-2
Exhibit 3-2: Stroke Management Products, Combined Market Forecast, 2014-2019 ……………………………………………………. 3-4
Exhibit 3-3: Stroke Diagnostic Imaging, Combined Procedure Volumes Forecast, 2014-2019 …………………………………………………. 3-7
Exhibit 3-4: Stroke Diagnostic Imaging Products, Combined Market Forecast, 2014-2019 ……………………………………………………. 3-9
Exhibit 3-5: Computed Tomography, Procedure Volumes Forecast, 2014-2019 ……………………………………………….. 3-13
Exhibit 3-6: Computed Tomography, Market Forecast, 2014-2019……………….. 3-14
Exhibit 3-7: 2014, Computed Tomography Systems Market, Share by Supplier ………………………………………………………………………….. 3-18
Exhibit 3-8: Magnetic Resonance Imaging, Procedure Volumes Forecast, 2014-2019 ……………………………………………….. 3-22
Exhibit 3-9: Magnetic Resonance Imaging, Market Forecast, 2014-2019 ………………………………………………….. 3-23
Exhibit 3-10: 2014, Magnetic Resonance Imaging Systems Market, Share by Supplier ………………………………………………………………………….. 3-26
Exhibit 3-11: Diagnostic Ultrasound Imaging, Procedure Volumes Forecast, 2014-2019 ……………………………………………….. 3-29
Exhibit 3-12: Diagnostic Ultrasound Imaging Systems, Market Forecast, 2014-2019 ………………………………………………….. 3-30
Exhibit 3-13: 2014, Diagnostic Ultrasound Imaging Systems Market, Share by Supplier ………………………………………………………………………….. 3-35
Exhibit 3-14: Nuclear Medicine Imaging, Procedure Volumes Forecast, 2014-2019 ……………………………………………….. 3-38
Exhibit 3-15: Nuclear Medicine Imaging Systems, Market Forecast, 2014-2019 ………………………………………………….. 3-39
Exhibit 3-16: 2014, Nuclear Medicine Imaging Systems Market, Share by Supplier ………………………………………………………………………….. 3-44
Exhibit 3-17: Cerebral Angiography, Procedure Volumes Forecast, 2014-2019 ……………………………………………….. 3-48
Exhibit 3-18: Cerebral Angiography Devices, Market Forecast, 2014-2019 ……… 3-49
Exhibit 3-19: 2014, Coronary Angiography Devices Market, Share by Supplier ………………………………………………………………………….. 3-50
Exhibit 3-20: Stroke-related Surgical and Endovascular Therapies, Combined Procedure Volumes Forecast, 2014-2019 ………………………………… 3-57
Exhibit 3-21: Stroke-related Surgical and Endovascular Therapies, Combined Market Forecast, 2014-2019 ………………………………………………….. 3-59
Exhibit 3-22: Carotid Endarterectomy, Procedure Volumes Forecast, 2014-2019 ……………………………………………….. 3-63
Exhibit 3-23: Carotid Endarterectomy, Market Forecast, 2014-2019……………….. 3-64
Exhibit 3-24: Distally Protected Carotid Artery Stenting, Procedure Volumes Forecast, 2014-2019 ……………………………………………….. 3-66
Exhibit 3-25: Distally Protected Carotid Artery Stenting, Market Forecast, 2014-2019 ………………………………………………….. 3-67
Exhibit 3-26: 2014, Distally Protected Carotid Artery Stenting Systems Market, Share by Supplier …………………………………………………………………. 3-69
Exhibit 3-27: Cerebral Aneurysm and Surgical AVM Repair, Procedure Volumes Forecast, 2014-2019 ……………………………………………….. 3-72
Exhibit 3-28: Cerebral Aneurysm and Surgical AVM Repair, Market Forecast, 2014-2019 ………………………………………………….. 3-73
Exhibit 3-29: 2014, Cerebral Aneurysm/AVM Clip Systems Market, Share by Supplier ………………………………………………………………………….. 3-74
Exhibit 3-30: Cerebral Aneurysm & AVM Endovascular Embolization, Procedure Volumes Forecast, 2014-2019 ………………………………… 3-77
Exhibit 3-31: Cerebral Aneurysm & AVM Endovascular Embolization, Market Forecast, 2014-2019 ………………………………………………….. 3-78
Exhibit 3-32: 2014, Cerebral Aneurysm & AVM Endovascular Embolization Systems Market, Share by Supplier ………………………………………… 3-79
Exhibit 3-33: Cerebral Thrombectomy, Procedure Volumes Forecast, 2014-2019 ……………………………………………….. 3-83
Exhibit 3-34: Cerebral Thrombectomy, Market Forecast, 2014-2019………………. 3-84
Exhibit 3-35: 2014, Cerebral Thrombectomy Systems Market, Share by Supplier ………………………………………………………………………….. 3-86
Exhibit 3-36: Intracranial Stenting, Market Forecast, 2014-2019…………………….. 3-89
APPENDIX: COMPANY LISTING……………………………………………………………… A-1
BIBLIOGRAPHY ……………………………………………………………………………………… B-1
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