Neurological impairment encompasses a diverse range of progressive centralnervous system (CNS) disorders that often are associated with significant psychiatricmorbidity and reduced quality of life. This report presents the prevalence and number of hospital discharges in the United States (U.S.) as well as the surgical procedure volumes for selected neurological diseases/disorders. Among the disorders covered by this report are Alzheimer’s disease, amyotrophic lateralsclerosis (ALS), bipolar disorder, cerebral aneurysm, depression, epilepsy,hydrocephalus, multiple sclerosis (MS), Parkinson’s disease, schizophrenia, andstroke. Among the covered surgical procedures are cerebrospinal fluid shunting,carotid artery stenting, cerebral aneurysm and arteriovenous malformation clipping and embolization, and intracranial stenting.
United States, Neurological Market Opportunities: Disease Incidence and Prevalence, and Surgical Procedure Volumes
United States, Neurological Market Opportunities: Disease Incidence and Prevalence, and Surgical Procedure Volumes
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This report presents the prevalence and number of hospital discharges in the United States (U.S.) as well as the surgical procedure volumes for selected neurological diseases/disorders.
Publisher: Medtech Insight
- Description
- Contents
- Samples
Table of Contents
1. OVERVIEW OF NEUROLOGICAL DISEASES/DISORDERS………………… 1-1
1.1 Alzheimer’s Disease……………………………………………………………….. 1-1
1.2 Amyotrophic Lateral Sclerosis ………………………………………………….. 1-3
1.3 Bipolar Disorder……………………………………………………………………… 1-3
1.4 Depression ……………………………………………………………………………. 1-4
1.5 Epilepsy………………………………………………………………………………… 1-5
1.6 Multiple Sclerosis……………………………………………………………………. 1-6
1.7 Parkinson’s Disease……………………………………………………………….. 1-7
1.8 Schizophrenia………………………………………………………………………… 1-7
1.9 Stroke…………………………………………………………………………………… 1-8
Exhibit 1-1: Neurosurgery, Procedure Volumes Forecast, by Type, 2011-2017… 1-2
Exhibit 1-2: Neurological Diseases/Disorders, Hospital Discharges
and Prevalence…………………………………………………………………….. 1-10
2. NEUROLOGICAL AND PSYCHIATRIC DISEASES/DISORDERS…………. 2-1
2.1 Alzheimer’s Disease……………………………………………………………….. 2-1
2.1.1 Etiology…………………………………………………………………… 2-3
2.1.2 Epidemiology…………………………………………………………… 2-4
2.2 Amyotrophic Lateral Sclerosis ………………………………………………….. 2-5
2.2.1 Etiology…………………………………………………………………… 2-6
2.2.2 Epidemiology…………………………………………………………… 2-8
2.3 Cerebrovascular Diseases/Disorders ………………………………………… 2-8
2.3.1 Arteriovenous Malformation……………………………………….. 2-8
2.3.1.1 Etiology ………………………………………………….. 2-10
2.3.1.2 Epidemiology…………………………………………… 2-10
2.3.2 Cerebral Aneurysm ………………………………………………… 2-10
2.3.2.1 Etiology ………………………………………………….. 2-12
2.3.2.2 Epidemiology…………………………………………… 2-12
2.3.3 Stroke…………………………………………………………………… 2-13
2.3.3.1 Etiology ………………………………………………….. 2-14
2.3.3.2 Epidemiology…………………………………………… 2-18
2.4 Epilepsy………………………………………………………………………………. 2-18
2.4.1 Etiology…………………………………………………………………. 2-19
2.4.2 Epidemiology…………………………………………………………. 2-21
2.5 Huntington’s Disease…………………………………………………………….. 2-22
2.5.1 Etiology…………………………………………………………………. 2-24
2.5.2 Epidemiology…………………………………………………………. 2-25
2.6 Hydrocephalus……………………………………………………………………… 2-25
2.6.1 Etiology…………………………………………………………………. 2-25
2.6.2 Epidemiology…………………………………………………………. 2-27
2.7 Multiple Sclerosis………………………………………………………………….. 2-27
2.7.1 Etiology…………………………………………………………………. 2-28
2.7.2 Epidemiology…………………………………………………………. 2-32
2.8 Myasthenia Gravis………………………………………………………………… 2-32
2.8.1 Etiology…………………………………………………………………. 2-34
2.8.2 Epidemiology…………………………………………………………. 2-35
2.9 Parkinson’s Disease……………………………………………………………… 2-35
2.9.1 Etiology…………………………………………………………………. 2-37
2.9.2 Epidemiology…………………………………………………………. 2-39
2.10 Psychiatric Disorders…………………………………………………………….. 2-40
2.10.1 Attention Deficient Hyperactivity Disorder ………………….. 2-40
2.10.1.1 Etiology ………………………………………………….. 2-42
2.10.1.2 Epidemiology…………………………………………… 2-44
2.10.2 Bipolar Disorder……………………………………………………… 2-46
2.10.2.1 Etiology ………………………………………………….. 2-46
2.10.2.2 Epidemiology…………………………………………… 2-49
2.10.3 Depression ……………………………………………………………. 2-50
2.10.3.1 Etiology ………………………………………………….. 2-50
2.10.3.2 Epidemiology…………………………………………… 2-54
2.10.4 Schizophrenia………………………………………………………… 2-55
2.10.4.1 Etiology ………………………………………………….. 2-56
2.10.4.2 Epidemiology…………………………………………… 2-58
Exhibit 2-1: Alzheimer’s Disease, Facts and Figures, 1999-2009, and 2010 and 2011…………………………………………………………………. 2-2
Exhibit 2-2: Amyotrophic Lateral Sclerosis, Facts and Figures, 1999-2009, and 2011 ……………………………………………………………… 2-7
Exhibit 2-3: Arteriovenous Malformation, Facts and Figures, 1999-2009, and 2011 ………………………………………………………………………………. 2-9
Exhibit 2-4: Cerebral Aneurysm, Facts and Figures, 1999-2009, and 2011 ……. 2-11
Exhibit 2-5: Stroke, Facts and Figures, 1999-2009, and 2010 and 2011………… 2-15
Exhibit 2-6: Epilepsy, Facts and Figures, 1999-2009, and 2011 …………………… 2-20
Exhibit 2-7: Huntington’s Disease, Facts and Figures …………………………………. 2-23
Exhibit 2-8: Hydrocephalus, Facts and Figures, 1999-2009, and 2011………….. 2-26
Exhibit 2-9: Multiple Sclerosis, Facts and Figures, 1999-2009, and 2011 ………. 2-29
Exhibit 2-10: Myasthenia Gravis, Facts and Figures, 1999-2009, and 2011 …….. 2-33
Exhibit 2-11: Parkinson’s Disease, Facts and Figures, 1999-2009, and 2011 ….. 2-36
Exhibit 2-12: Percentage of Adults Experiencing Serious
Psychological Distress, by Age and Gender……………………………… 2-41
Exhibit 2-13: Attention Deficit Hyperactivity Disorder, Facts and Figures,
1999-2009, and 2011 ……………………………………………………………. 2-43
Exhibit 2-14: Bipolar Disorder, Facts and Figures, 1999-2009, and 2011 ………… 2-47
Exhibit 2-15: Depression, Facts and Figures, 1999-2009, and 2011……………….. 2-51
Exhibit 2-16: Schizophrenia, Facts and Figures, 1999-2009, and 2011 …………… 2-57
3. NEUROSURGICAL PROCEDURES ………………………………………………….. 3-1
3.1 Stroke…………………………………………………………………………………… 3-1
3.1.1 Hemorrhagic Stroke………………………………………………….. 3-1
3.1.2 Ischemic Stroke……………………………………………………….. 3-3
3.2 Cerebral Aneurysm…………………………………………………………………. 3-5
3.3 Arteriovenous Malformations……………………………………………………. 3-6
3.4 Tumors of the Brain and Central Nervous System ………………………. 3-7
3.5 Traumatic Brain Injury …………………………………………………………….. 3-9
3.6 Hydrocephalus and Increased Intracranial Pressure………………….. 3-10
3.7 Neurosurgical Procedures ……………………………………………………… 3-12
3.7.1 Cerebrospinal Fluid Shunting and Drainage……………….. 3-12
3.7.1.1 Procedure Volumes………………………………….. 3-14
3.7.2 Carotid Endarterectomy…………………………………………… 3-14
3.7.2.1 Procedure Volumes………………………………….. 3-16
3.7.3 Cerebral Aneurysm and Arteriovenous Malformation Surgical Clipping…………………………………. 3-16
3.7.3.1 Procedure Volumes………………………………….. 3-19
3.7.4 Cerebral Aneurysm and Arteriovenous Malformation Embolization ………………………………………. 3-20
3.7.4.1 Procedure Volumes………………………………….. 3-22
3.7.5 Carotid Artery Stenting ……………………………………………. 3-22
3.7.5.1 Carotid Revascularization Endarterectomy versus Stenting Trial Results……………………… 3-24
3.7.5.2 Procedure Volumes………………………………….. 3-26
3.7.6 Intracranial Stenting………………………………………………… 3-28
3.7.6.1 Procedure Volumes………………………………….. 3-29
Exhibit 3-1: Cerebrospinal Fluid Shunting, Procedure Volumes Forecast, 2011-2017 …………………………………………………………………………… 3-15
Exhibit 3-2: Carotid Endarterectomy, Procedure Volumes Forecast, 2011-2017 …………………………………………………………………………… 3-17
Exhibit 3-3: Cerebral Aneurysm and Arteriovenous Malformation Surgical Clipping, Procedure Volumes Forecast, 2011-2017 ………. 3-21
Exhibit 3-4: Cerebral Aneurysm and Arteriovenous Malformation
Embolization, Procedure Volumes Forecast, 2011-2017…………….. 3-23
Exhibit 3-5: Distally Protected Carotid Artery Stenting, Procedure Volumes Forecast, 2011-2017 ………………………………… 3-27
Exhibit 3-6: Intracranial Stenting, Procedure Volumes Forecast, 2011-2017 ….. 3-31
Figure: Neurosurgery, Procedure Volumes Forecast, by Type, 2011-2017
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