US Neurointerventional Devices Market
US Neurointerventional Devices Market
$4,750.00
Neurointerventional radiology/surgery, or neurovascular intervention, is a relatively new medical specialty employing minimally invasive endovascular techniques to treat vascular diseases of the brain. Neurointerventional devices, which contributed sales of more than $870m in the US in 2015, involve a variety of standard and application-specific transcatheter tools and techniques for the treatment of cerebrovascular pathologies (such as aneurysms, arteriovenous malformations [AVMs], and acute and chronic thromboembolic and atherosclerotic occlusions) that prompt clinically significant distortions of cerebral blood flow and carry a high risk of catastrophic breakdowns of cerebrovascular circulation manifested by hemorrhagic or ischemic stroke.
Publisher: Meddevicetracker
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Neurointerventional radiology/surgery, or neurovascular intervention, is a relatively new medical specialty employing minimally invasive endovascular techniques to treat vascular diseases of the brain. Neurointerventional devices, which contributed sales of more than $870m in the US in 2015, involve a variety of standard and application-specific transcatheter tools and techniques for the treatment of cerebrovascular pathologies (such as aneurysms, arteriovenous malformations [AVMs], and acute and chronic thromboembolic and atherosclerotic occlusions) that prompt clinically significant distortions of cerebral blood flow and carry a high risk of catastrophic breakdowns of cerebrovascular circulation manifested by hemorrhagic or ischemic stroke.
The scope of neurointerventional device market analysis offered in this report includes the following medical devices sold in the US:
- endovascular/transcatheter embolization systems for cerebral aneurysms and AVMs
- adjuvant embolic coil-containment stenting for the management of wide-neck aneurysms
- novel specialty stent graft-based flow redirection, or flow-diversion devices for large wide-neck aneurysms
- carotid artery stent (CAS) systems for treatment of high-grade carotid stenosis
- mechanical cerebral thrombectomy systems targeting selected patient subsets with acute ischemic stroke
EXECUTIVE SUMMARY…………………………………………………………………………. ES-1
i. Clinical Overview of Neurovascular Disease ……………………………. ES-1
a. Arteriovenous Malformations…………………………………… ES-1
b. Brain Aneurysms …………………………………………………… ES-2
c. Stroke………………………………………………………………….. ES-2
ii. US Neurointerventional Devices Market………………………………….. ES-3
iii. Market Forecasts, by Segment………………………………………………. ES-4
iv. Methodology……………………………………………………………………….. ES-6
Exhibit ES-1: US Neurointerventional Devices Market Forecast, by Therapy Segment ($m), 2015–20………………………………………. ES-7
Exhibit ES-2: US Neurointerventional Devices Market, Estimated Percentage of Sales, by Type of Therapy, 2015 ………………………. ES-9
Exhibit ES-3: US Neurointerventional Devices Market, Estimated Percentage of Sales, by Type of Therapy, 2020 …………………….. ES-10
1. CEREBRAL ANEURYSM AND AVM EMBOLIZATION SYSTEMS MARKET………………………………………………………………………………………… 1-1
1.1 Microcoils ……………………………………………………………………………… 1-3
1.1.1 Blockade Medical …………………………………………………….. 1-4
1.1.2 Codman Neuro/DePuy Synthes …………………………………. 1-4
1.1.3 Medtronic (Covidien) ………………………………………………… 1-4
1.1.4 MicroVention-Terumo……………………………………………….. 1-4
1.1.5 Stryker ……………………………………………………………………. 1-5
1.2 Liquid Embolics ……………………………………………………………………… 1-5
1.2.1 Medtronic………………………………………………………………… 1-7
1.2.2 Codman Neuro/DePuy Synthes …………………………………. 1-7
1.3 The ARUBA Trial……………………………………………………………………. 1-8
1.4 Market Forecast……………………………………………………………………… 1-9
1.5 Competitive Analysis …………………………………………………………….. 1-10
Exhibit 1-1: Stryker’s Target Nano and Target 360 Detachable Coils ……………… 1-6
Exhibit 1-2: Cerebral Aneurysm and AVM Endovascular Embolization Systems Market Forecast, 2015–20………………………………………… 1-11
Exhibit 1-3: Cerebral Aneurysm and AVM Endovascular Embolization Systems Market, Share by Supplier, 2015 ……………………………….. 1-13
2. WIDE-NECK CEREBRAL ANEURYSM EMBOLIZATION-ENABLING STENT SYSTEMS MARKET…………………………………………………………….. 2-1
2.1 Adjuvant Embolic Coil-Containment Stenting Systems ………………… 2-1
2.1.1 Codman Neuro/DePuy Synthes …………………………………. 2-2
2.1.2 Stryker ……………………………………………………………………. 2-3
2.2 Flow-Diversion Devices …………………………………………………………… 2-3
2.2.1 Medtronic………………………………………………………………… 2-3
2.2.2 Sequent Medical/MicroVention-Terumo ………………………. 2-6
2.2.3 Others…………………………………………………………………….. 2-7
2.2.3.1 Acandis GmbH ………………………………………….. 2-7
2.2.3.2 InspireMD…………………………………………………. 2-7
2.2.3.3 MicroVention-Terumo…………………………………. 2-9
2.2.3.4 Phenox GmbH…………………………………………… 2-9
2.2.3.5 Stryker……………………………………………………… 2-9
2.3 Market Forecast……………………………………………………………………… 2-9
2.4 Competitive Analysis …………………………………………………………….. 2-13
Exhibit 2-1: Stryker’s Neuroform EZ Stent…………………………………………………… 2-4
Exhibit 2-2: Sequent Medical/MicroVention-Terumo’s WEB…………………………… 2-8
Exhibit 2-3: Wide-Neck Cerebral Aneurysm Embolization-Enabling Stent Systems Market Forecast, 2015–20………………………………………… 2-11
Exhibit 2-4: Wide-Neck Cerebral Aneurysm Embolization-Enabling Stent Systems Market, Share by Supplier, 2015 ……………………………….. 2-14
3. CAROTID ARTERY STENT SYSTEMS MARKET……………………………….. 3-1
3.1 Carotid Artery Stent Systems …………………………………………………… 3-1
3.1.1 Abbott Vascular/Abbott Laboratories…………………………… 3-2
3.1.2 Boston Scientific………………………………………………………. 3-4
3.1.3 Cordis/Cardinal Health ……………………………………………… 3-4
3.1.4 Medtronic………………………………………………………………… 3-4
3.1.5 MicroVention-Terumo……………………………………………….. 3-4
3.2 Embolic Protection Systems…………………………………………………….. 3-5
3.2.1 Allium Medical Solutions……………………………………………. 3-7
3.2.2 Cordis/Cardinal Health ……………………………………………… 3-8
3.2.3 InspireMD……………………………………………………………….. 3-8
3.2.4 Medtronic………………………………………………………………… 3-9
3.2.5 Silk Road Medical…………………………………………………….. 3-9
3.3 CREST Trial Results …………………………………………………………….. 3-11
3.4 Market Forecast……………………………………………………………………. 3-14
3.5 Competitive Analysis …………………………………………………………….. 3-17
Exhibit 3-1: Abbott Laboratories’ RX Acculink Carotid Stent System, RX Accunet and Emboshield NAV6 Embolic Protection Systems ……….. 3-3
Exhibit 3-2: MicroVention-Terumo’s Roadsaver Carotid Artery Stent System…… 3-6
Exhibit 3-3: Medtronic’s SpiderFX ……………………………………………………………. 3-10
Exhibit 3-4: Carotid Artery Stent Systems, Market Forecast, 2015–20…………… 3-16
Exhibit 3-5: Carotid Artery Stent Systems Market, Share by Supplier, 2015 …… 3-18
4. CEREBRAL THROMBECTOMY SYSTEMS MARKET…………………………. 4-1
4.1 Medtronic………………………………………………………………………………. 4-2
4.2 Penumbra……………………………………………………………………………… 4-5
4.3 Stryker ………………………………………………………………………………….. 4-6
4.4 Other Emerging Devices …………………………………………………………. 4-9
4.4.1 Acandis GmbH ………………………………………………………… 4-9
4.4.2 Codman/Johnson & Johnson …………………………………….. 4-9
4.4.3 Neuravi …………………………………………………………………. 4-10
4.4.4 MicroVention-Terumo……………………………………………… 4-10
4.4.5 Phenox GmbH……………………………………………………….. 4-11
4.5 Selected Clinical Trials ………………………………………………………….. 4-11
4.6 2015 AHA/ASA Recommendations for Endovascular Treatment/Mechanical Thrombectomy …………………………………….. 4-14
4.7 Market Forecast……………………………………………………………………. 4-15
4.8 Competitive Analysis ……………………………………………………………….. 4-19
Exhibit 4-1: Medtronic’s Solitaire FR Revascularization Device ……………………… 4-3
Exhibit 4-2: Stryker’s Trevo XP ProVue Retriever Featuring a Distal FlexCell Design ……………………………………………………………………… 4-8
Exhibit 4-3: Cerebral Thrombectomy Systems Market Forecast, 2015–20 …….. 4-18
Exhibit 4-4: Cerebral Thrombectomy Systems Market, Share by Supplier, 2015 ……………………………………………………………………… 4-20
APPENDIX A: COMPANY LISTING
APPENDIX B: BIBLIOGRAPHY
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