Vyxeos (cytarabine/daunorubicin; Jazz Pharmaceuticals) is a liposomal formulation of a 5:1 molar ratio of cytarabine and daunorubicin – chemotherapy drugs which are currently administered as two separate intravenous injections as part of the 7+3 regimen for the treatment of acute myeloid leukemia. The delivery of cytarabine/daunorubicin combination therapy to cancer cells at this fixed ratio is thought to optimize anti-cancer activity, and encapsulation of the drugs in the liposome increases the time that the patient is exposed to the drug post-administration.
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